Evidence map›Paper›PMID 36594584›Full record

ArticleJournal of biomedical materials research. Part A2023

Derivatization of graphene oxide nanosheets with tunable nitric oxide release for antibacterial biomaterials.

Mark Garren, Morgan Ashcraft, Dagney Crowley, Elizabeth J Brisbois, Hitesh Handa

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Graphene Oxide: Preparation and Medical Research.Materials (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Wearable nitric oxide-releasing antibacterial insert for preventing device-associated infections.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Mark Garren *School of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID 0000-0001-5194-6558
Morgan Ashcraft *Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, USA.ORCID 0000-0001-5532-086X
Dagney CrowleySchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.
Elizabeth J BrisboisSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-9283-5448
Hitesh HandaSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-9369-7374
University of Georgia · US

Funding

Engineering nitric oxide releasing polymer with immobilized thrombin inhibitor for blood contacting applicationsR01HL134899 · NHLBI · UNIVERSITY OF GEORGIA · PI HANDA, HITESH · 2017 to 2025
$3.0M
Heparin-free extracorporeal circulation via combined nitric oxide releasing/generating surfacesR01HL157587 · NHLBI · UNIVERSITY OF GEORGIA · PI BRISBOIS, ELIZABETH JOY · 2021 to 2024
$1.5M
National Science Foundation 1842396NHLBI NIH HHS R01 HL134899NHLBI NIH HHS R01 HL157587
6 · The paper itself

Abstract

Graphene oxide (GO) nanosheets are a promising class of carbon-based materials suitable for application in the construction of medical devices. These materials have inherent antimicrobial properties based on sheet size, but these effects must be carefully traded off to maintain biocompatibility. Chemical modification of functional groups to the lattice structure of GO nanosheets enables unique opportunities to introduce new surface properties to bolster biological effects. Herein, we have developed nitric oxide (NO)-releasing GO nanosheets via immobilization of S-nitrosothiol (RSNO) moieties to GO nanosheets (GO-[NH]

Indexed as

Biocompatible MaterialsGraphiteAnti-Bacterial AgentsHumansNitric OxideAnti-Bacterial AgentsBiocompatible Materialsgraphene oxideGraphiteNitric Oxideantimicrobialgraphene oxidenitric oxide

Identifiers

PMID36594584
PMCPMC9936865
OpenAlexW4313439080

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.