Evidence map›Paper›PMID 36598065›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

The value of serum TRAP1 in diagnosing small cell lung cancer and tumor immunity.

Li-Ming Tan, Shi-Peng Ke, Xu Li, Tang-Lin Ouyang, Li-Qing Yu, Jia-Li Yu, Ya-Kun Wang, Qi-Jun Yang, Xiao-Hang Li, Xia Yu and 2 more

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review: Detection of Cancer Biomarkers from a Clinical Perspective.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Li-Ming TanJiangxi Province Key Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.ORCID 0000-0002-1888-3476
Shi-Peng KeThe Second Clinical Medical School, Nanchang University, Nanchang 330006, China.
Xu LiJiangxi Province Key Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Tang-Lin OuyangSchool of Public Health, Nanchang University, Nanchang 330031, China.
Li-Qing YuThe Second Clinical Medical School, Nanchang University, Nanchang 330006, China.
Jia-Li YuThe Second Clinical Medical School, Nanchang University, Nanchang 330006, China.
Ya-Kun WangThe Second Clinical Medical School, Nanchang University, Nanchang 330006, China.
Qi-Jun YangQueen Mary College, Nanchang University, Nanchang 330001, China.
Xiao-Hang LiJiangxi Province Key Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Xia YuThe Second Clinical Medical School, Nanchang University, Nanchang 330006, China.
Hua LiJiangxi Province Key Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Xiao-Yan HuJiangxi Province Key Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study set out to investigate the clinical significance of serum tumor necrosis factor receptor-associated protein 1 (TRAP1) in diagnosing small cell lung cancer (SCLC) with different clinical stages, and to compare the diagnostic efficiency with neuron-specific enolase (NSE), carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9). Besides, to analyze the role of serum TRAP1 in tumor immunity. A total of 91 patients with SCLC, 99 patients with non-small cell lung cancer (NSCLC), 102 patients with pulmonary nodules (PN), and 75 healthy people were included. The concentrations of serum TRAP1 was detected by enzyme-linked immunosorbent assay (ELISA). NSE, CEA, and CA19-9 were detected by chemiluminescence. The results showed that level of TRAP1 in Group SCLC was lower than other three groups (

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsBiomarkers, TumorCA-19-9 AntigenCarcinoembryonic AntigenHSP90 Heat-Shock ProteinsHumansBiomarkers, TumorCA-19-9 AntigenCarcinoembryonic AntigenHSP90 Heat-Shock ProteinsTRAP1 protein, humanclinical stagecombined diagnosisSCLCTRAP1tumor immunity

Identifiers

PMID36598065
PMCPMC10107397
OpenAlexW4313488172

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.