Evidence map›Paper›PMID 36598241›Full record

ArticlemSystems2023

Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome.

Ulrika Beitnere, Brayan Vilanova-Cuevas, Sarah G Christian, Clint Taylor, Elizabeth L Berg, Nycole A Copping, Scott V Dindot, Jill L Silverman, Mélanie G Gareau, David J Segal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ulrika Beitnere *Genome Center, University of California Davis, Davis, California, USA.
Brayan Vilanova-Cuevas *Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, USA.
Sarah G ChristianDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.
Clint TaylorDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.
Elizabeth L BergDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, California, USA.
Nycole A CoppingDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, California, USA.
Scott V DindotDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.
Jill L SilvermanDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, California, USA.
Mélanie G GareauDepartment of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, USA.ORCID 0000-0001-6008-6975
David J SegalGenome Center, University of California Davis, Davis, California, USA.
University of California, Davis · USTexas A&M University · US

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Postbaccalaureate Research Education Program at UC DavisR25GM116690 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOANNA Chungyen CHIU · 2017 to 2026
$3.7M
Phenotypic Characterization of Novel Models of Dup15q SyndromeR01NS097808 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SILVERMAN, JILL LYNN · 2017 to 2021
$1.7M
NICHD NIH HHS P50 HD103526NIGMS NIH HHS R25 GM116690NINDS NIH HHS R01 NS097808
6 · The paper itself

Abstract

A large subset of patients with Angelman syndrome (AS) suffer from concurrent gastrointestinal (GI) issues, including constipation, poor feeding, and reflux. AS is caused by the loss of ubiquitin ligase E3A (

Indexed as

Angelman SyndromeGastrointestinal DiseasesGastrointestinal MicrobiomeAnimalsDisease Models, AnimalMiceQuality of LifeRatsRNA, Ribosomal, 16SSwineUbiquitin-Protein LigasesRNA, Ribosomal, 16SUbe3a protein, ratUbiquitin-Protein Ligases16S rRNA gene sequencingAngelman syndromeanimal modelsbacterial metabolitesgut-brain axisgut microbiomemicrobiotaneurodevelopmental disorders

Identifiers

PMID36598241
PMCPMC9948700
OpenAlexW4313488859

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.