Evidence map›Paper›PMID 36598465›Full record

ArticleJournal of medicinal chemistry2023

[1,2,4]Triazolo[3,4-

Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Sudarshan MurthyFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
Maria Giulia NiziDepartment of Pharmaceutical Sciences, University of Perugia, Perugia06123, Italy.
Mirko M MaksimainenFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
Serena MassariDepartment of Pharmaceutical Sciences, University of Perugia, Perugia06123, Italy.ORCID 0000-0002-9992-6318
Juho AlaviuhkolaFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
Barbara E LippokInstitute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen52074, Germany.
Chiara VagagginiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, SienaI-53100, Italy.
Sven T SowaFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
Albert Galera-PratFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
Yashwanth AshokFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.ORCID 0000-0002-5693-6372
Harikanth VenkannagariFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.ORCID 0000-0001-9769-2303
Renata Prunskaite-HyyryläinenFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
Elena DreassiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, SienaI-53100, Italy.
Bernhard LüscherInstitute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen52074, Germany.ORCID 0000-0002-9622-8709
Patricia KornInstitute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen52074, Germany.
Oriana TabarriniDepartment of Pharmaceutical Sciences, University of Perugia, Perugia06123, Italy.ORCID 0000-0003-2693-5675
Lari LehtiöFaculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.ORCID 0000-0001-7250-832X
University of Oulu · FIRWTH Aachen University · DEUniversity of Perugia · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report [1,2,4]triazolo[3,4-

Indexed as

Poly(ADP-ribose) Polymerase InhibitorsTankyrasesBenzothiazolesDrug DevelopmentHumansNiacinamidePoly(ADP-ribose) PolymerasesProto-Oncogene ProteinsBenzothiazolesNiacinamidePARP10 protein, humanPoly(ADP-ribose) Polymerase InhibitorsPoly(ADP-ribose) PolymerasesProto-Oncogene ProteinsTankyrasesTNKS2 protein, human

Identifiers

PMID36598465
PMCPMC9884089
OpenAlexW4313488259

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.