Evidence map›Paper›PMID 36600608›Full record

ReviewOpen heart2022

Coronary endothelial dysfunction: from pathogenesis to clinical implications.

Lee Bockus, Francis Kim

Open access · goldAbstract readReview
In one paragraph

Review in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. The role of ferroptosis in vascular endothelial cells and its role in the pathogenesis of cervical spondylosis of vertebral artery type: a comprehensive review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lee BockusDeparment of Medicine, University of Washington, Seattle, Washington, USA.
Francis KimDeparment of Medicine, University of Washington, Seattle, Washington, USA fkim@u.washington.edu.ORCID 0000-0001-5398-6254
University of Washington · US

Funding

Red Blood Cell Endothelial Nitric Oxide Attenuates Insulin ResistanceR01HL139555 · NHLBI · UNIVERSITY OF WASHINGTON · PI KIM, FRANCIS · 2018 to 2021
$2.2M
Endothelial nitric oxide synthase and regulation of macrophage functionR01DK106703 · NIDDK · UNIVERSITY OF WASHINGTON · PI KIM, FRANCIS · 2016 to 2019
$1.8M
NHLBI NIH HHS R01 HL139555NIDDK NIH HHS R01 DK106703
6 · The paper itself

Abstract

Endothelial dysfunction (ED) has a substantial role in the pathogenesis of atherosclerosis and other vascular diseases. Multiple risk factors, including smoking, hyperlipiadaemia and diabetes, can have associated ED, which is correlated with cardiac events. Measurement of coronary artery endothelial function requires the use of invasive techniques to assess both epicardial coronary artery and microvascular beds. Peripheral vascular techniques and endothelial biomarkers can be used to indirectly assess coronary ED. In this review of coronary artery ED, we discuss the current state of the field, the techniques used to measure ED and its clinical implications.

Indexed as

AtherosclerosisCoronary Artery DiseaseEndothelium, VascularHeartHumansAtherosclerosisCORONARY ARTERY DISEASEMicrovascular AnginaRISK FACTORS

Identifiers

PMID36600608
PMCPMC9743399
OpenAlexW4310920015

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.