Evidence map›Paper›PMID 36600772›Full record

ArticleSurgical neurology international2022

Histological changes of vascular clipping in Wistar rats.

Jonathan Samuel Zúñiga Córdova, Mickaela Echavarría Demichelis, Forlizzi Valeria, Gustavo Garavaglia, Feres Chaddad, Carlos Castillo Rangel, Jaime Ordóñez-Granja, Alvaro Campero, Gerardo Marín, Matias Baldoncini

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Jonathan Samuel Zúñiga CórdovaDepartment of Neurosurgery, ISSSTE, Mexico City, Mexico.
Mickaela Echavarría DemichelisDepartment of Neurosurgery, Hospital Petrona V. de Cordero, San Fernando.
Forlizzi ValeriaLaboratory of Microsurgical Neuroanatomy, Second Chair of Gross Anatomy, School of Medicine, University of Buenos Aires, Buenos Aires.
Gustavo GaravagliaDepartment of Pathology of the Faculty of Medicine, Buenos Aires University, Buenos Aires, Argentina.
Feres ChaddadDepartment of Neurosurgery, Sao Paulo Federal University, Sao Paulo, Brazil.
Carlos Castillo RangelDepartment of Neurosurgery, ISSSTE, Mexico City, Mexico.
Jaime Ordóñez-GranjaDepartment of Neurosurgery, ISSSTE, Mexico City, Mexico.
Alvaro CamperoDepartment of Neurosurgery, Hospital Padilla de Tucuman, San Miguel de Tucuman, Argentina.
Gerardo MarínNeural Dynamics and Modulation Lab, Cleveland Clinic, Ohio, United States.
Matias BaldonciniLaboratory of Microsurgical Neuroanatomy, Second Chair of Gross Anatomy, University of Buenos Aires, Buenos Aires, Argentina.
Institute for Social Security and Services for State Workers · MXUniversity of Buenos Aires · ARCleveland Clinic · USUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: During aneurysm microsurgery, the aneurysmal sac is excluded from circulation by placing one or more clips at the base of the aneurysm. In some cases of complex aneurysms or subarachnoid hemorrhage history, transient clipping before definitive clipping is necessary. The closing force of the transient clip is less than the permanent clip; however, it is sufficient to stop circulation to the aneurysmal sac. The aim of the following work is to analyze and describe histological changes caused by transient and permanent clipping of the abdominal aorta in Wistar-type rats, to study the correlation between the closing force of the clip and the time, it remains on the vascular tissue structures. Methods: Six groups were formed, with 10 rats each, whereby temporary clipping of the abdominal aorta was performed with subsequent sampling of the site where the vascular clip was placed. The groups were: control and temporary clipping with: 2, 5, 10, and 15 and permanent clipping with 5 min. Results: Resection samples of the 3 μm thick aorta were obtained through the routine histological technique and special histochemical techniques (Masson's Trichrome and orcein) from the six groups. Transmural changes were found from Group II-VI. Conclusion: There is a vascular histological effect after both transient and permanent clipping. The sum of time and strength of the clip induce vascular changes visible at 5 min.

Indexed as

Endothelial lesionHistological changesNeuropathologyVascular clippingWistar rats

Identifiers

PMID36600772
PMCPMC9805646
OpenAlexW4311193982

What Socratic holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.