Evidence map›Paper›PMID 36601040›Full record

ArticleEuropean urology open science2023

Automated Patient-level Prostate Cancer Detection with Quantitative Diffusion Magnetic Resonance Imaging.

Allison Y Zhong, Leonardino A Digma, Troy Hussain, Christine H Feng, Christopher C Conlin, Karen Tye, Asona J Lui, Maren M S Andreassen, Ana E Rodríguez-Soto, Roshan Karunamuni and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European urology open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Urethra contours on MRI: Multidisciplinary consensus educational atlas and reference standard for artificial intelligence benchmarking.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2026
    Article
  10. Article
  11. Article
  12. Quantitative Prostate MRI, From theAJR. American journal of roentgenology · 2025
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Comparison of synthesized and acquired high b-value diffusion-weighted MRI for detection of prostate cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Allison Y ZhongDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Leonardino A DigmaDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Troy HussainDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Christine H FengDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Christopher C ConlinDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Karen TyeDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Asona J LuiDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Maren M S AndreassenDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Ana E Rodríguez-SotoDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Roshan KarunamuniDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Joshua KupermanDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Christopher J KaneDepartment of Urology, University of California San Diego, La Jolla, CA, USA.
Rebecca Rakow-PennerDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Michael E HahnDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Anders M DaleDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Tyler M SeibertDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
University of California, San Diego · USLa Jolla Bioengineering Institute · USNorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multiparametric magnetic resonance imaging (mpMRI) improves detection of clinically significant prostate cancer (csPCa), but the subjective Prostate Imaging Reporting and Data System (PI-RADS) system and quantitative apparent diffusion coefficient (ADC) are inconsistent. Restriction spectrum imaging (RSI) is an advanced diffusion-weighted MRI technique that yields a quantitative imaging biomarker for csPCa called the RSI restriction score (RSI Objective: To evaluate RSI Design setting and participants: We retrospectively studied all patients ( Intervention: We calculated the maximum RSI Outcome measurements and statistical analysis: We compared the performance of RSI Results and limitations: AUC values for ADC, RSI Conclusions: RSI Patient summary: We evaluated a rapid, advanced prostate magnetic resonance imaging technique called restriction spectrum imaging to see whether it could give an automated score that predicted the presence of clinically significant prostate cancer. The automated score worked about as well as expert radiologists' interpretation. The combination of the radiologists' scores and automated score might be better than either alone.

Indexed as

CancerDiffusion magnetic resonance imagingProstateQuantitative magnetic resonance imagingRestriction spectrum imaging

Identifiers

PMID36601040
PMCPMC9806706
OpenAlexW4311617340

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.