Evidence map›Paper›PMID 36606250›Full record

ReviewBioactive materials2023

Structural and biological engineering of 3D hydrogels for wound healing.

Mohammad Hadi Norahan, Sara Cristina Pedroza-González, Mónica Gabriela Sánchez-Salazar, Mario Moisés Álvarez, Grissel Trujillo de Santiago

Abstract readReview
In one paragraph

Review in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed.

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  14. Enhancing Wound Healing with a Novel Alginate/Eggshell Membrane-Based Hydrogel Enriched with Red Ginseng Roots and Centella Asiatica.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Hadi NorahanEscuela de Ingeniería y Ciencias, Tecnológico de Monterrey, Monterrey, NL, 64849, Mexico.
Sara Cristina Pedroza-GonzálezEscuela de Ingeniería y Ciencias, Tecnológico de Monterrey, Monterrey, NL, 64849, Mexico.
Mónica Gabriela Sánchez-SalazarCentro de Biotecnología-FEMSA, Tecnológico de Monterrey, Monterrey, Nuevo León, CP, 64849, Mexico.
Mario Moisés ÁlvarezCentro de Biotecnología-FEMSA, Tecnológico de Monterrey, Monterrey, Nuevo León, CP, 64849, Mexico.
Grissel Trujillo de SantiagoEscuela de Ingeniería y Ciencias, Tecnológico de Monterrey, Monterrey, NL, 64849, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds have become one of the most important issues for healthcare systems and are a leading cause of death worldwide. Wound dressings are necessary to facilitate wound treatment. Engineering wound dressings may substantially reduce healing time, reduce the risk of recurrent infections, and reduce the disability and costs associated. In the path of engineering of an ideal wound dressing, hydrogels have played a leading role. Hydrogels are 3D hydrophilic polymeric structures that can provide a protective barrier, mimic the native extracellular matrix (ECM), and provide a humid environment. Due to their advantages, hydrogels (with different architectural, physical, mechanical, and biological properties) have been extensively explored as wound dressing platforms. Here we describe recent studies on hydrogels for wound healing applications with a strong focus on the interplay between the fabrication method used and the architectural, mechanical, and biological performance achieved. Moreover, we review different categories of additives which can enhance wound regeneration using 3D hydrogel dressings. Hydrogel engineering for wound healing applications promises the generation of smart solutions to solve this pressing problem, enabling key functionalities such as bacterial growth inhibition, enhanced re-epithelialization, vascularization, improved recovery of the tissue functionality, and overall, accelerated and effective wound healing.

Indexed as

3D cultureHydrogelTissue engineeringWound dressingWound healing

Identifiers

PMID36606250
PMCPMC9803907

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.