Evidence map›Paper›PMID 36612097›Full record

ReviewCancers2022

Current Status of Research on Small Extracellular Vesicles for the Diagnosis and Treatment of Urological Tumors.

Mengting Zhang, Yukang Lu, Lanfeng Wang, Yiping Mao, Xinyi Hu, Zhiping Chen

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mengting ZhangThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0001-6158-1513
Yukang LuThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Lanfeng WangDepartment of Nephrology, First Affiliated Hospital of Gannan Medical University, Ganzhou 341000, China.
Yiping MaoThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Xinyi HuThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Zhiping ChenThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Gannan Medical University · CNFirst Affiliated Hospital of Gannan Medical University · CN

Funding

Health Commission of Jiangxi Province 202210860Health Commission of Jiangxi Province 202310839Natural Science Foundation of Jiangxi Province 20202BABL206119
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are important mediators of communication between tumor cells and normal cells. These vesicles are rich in a variety of contents such as RNA, DNA, and proteins, and can be involved in angiogenesis, epithelial-mesenchymal transition, the formation of pre-metastatic ecological niches, and the regulation of the tumor microenvironment. Small extracellular vesicles (sEVs) are a type of EVs. Currently, the main treatments for urological tumors are surgery, radiotherapy, and targeted therapy. However, urological tumors are difficult to diagnose and treat due to their high metastatic rate, tendency to develop drug resistance, and the low sensitivity of liquid biopsies. Numerous studies have shown that sEVs offer novel therapeutic options for tumor treatment, such as tumor vaccines and tumor drug carriers. sEVs have attracted a great deal of attention owing to their contribution to in intercellular communication, and as novel biomarkers, and role in the treatment of urological tumors. This article reviews the research and applications of sEVs in the diagnosis and treatment of urological tumors.

Indexed as

angiogenesisdrug carrierssmall extracellular vesiclestumor vaccinesurological tumors

Identifiers

PMID36612097
PMCPMC9817817
OpenAlexW4313245286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.