Evidence map›Paper›PMID 36613577›Full record

ArticleInternational journal of molecular sciences2022

Spectrofluorimetric and Computational Investigation of New Phthalimide Derivatives towards Human Neutrophil Elastase Inhibition and Antiproliferative Activity.

Beata Donarska, Marta Świtalska, Joanna Wietrzyk, Wojciech Płaziński, Krzysztof Z Łączkowski

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Beata DonarskaDepartment of Chemical Technology and Pharmaceuticals, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Jurasza 2, 85-089 Bydgoszcz, Poland.
Marta ŚwitalskaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wrocław, Poland.
Joanna WietrzykHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wrocław, Poland.ORCID 0000-0003-4980-6606
Wojciech PłazińskiJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, 30-239 Cracow, Poland.
Krzysztof Z ŁączkowskiDepartment of Chemical Technology and Pharmaceuticals, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Jurasza 2, 85-089 Bydgoszcz, Poland.ORCID 0000-0003-2107-2719
Ludwik Hirszfeld Institute of Immunology and Experimental Therapy · PLNicolaus Copernicus University · PLMedical University of Lublin · PL

Funding

Nicolaus Copernicus University WF 540/2020
6 · The paper itself

Abstract

Herein, nine phthalimide-based thiazoles (

Indexed as

Antineoplastic AgentsNeoplasmsCell ProliferationDrug Screening Assays, AntitumorHumansLeukocyte ElastaseMolecular StructurePhthalimidesSpectrometry, FluorescenceStructure-Activity RelationshipAntineoplastic AgentsLeukocyte ElastasePhthalimidesantiproliferative activityhuman neutrophil elastasephthalimidespectrofluorimetric methodthiazole

Identifiers

PMID36613577
PMCPMC9820738
OpenAlexW4312186420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.