Evidence map›Paper›PMID 36613985›Full record

ArticleInternational journal of molecular sciences2022

A Novel Biocidal Nanocomposite: Spherical Silica with Silver Ions Anchored at the Surface.

Magdalena Laskowska, Paweł Kowalczyk, Agnieszka Karczmarska, Karol Kramkowski, Karol Wrzosek, Łukasz Laskowski

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Magdalena LaskowskaInstitute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow, Poland.ORCID 0000-0001-9106-9756
Paweł KowalczykDepartment of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, PL-05110 Jabłonna, Poland.ORCID 0000-0003-4025-3750
Agnieszka KarczmarskaInstitute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow, Poland.ORCID 0000-0001-5121-5368
Karol KramkowskiDepartment of Physical Chemistry, Medical University of Bialystok, PL-15089 Białystok, Poland.
Karol WrzosekDepartment of Heart Diseases, The Medical Center of Postgraduate Education, PL-01813 Warszawa, Poland.ORCID 0000-0003-2261-7127
Łukasz LaskowskiInstitute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow, Poland.ORCID 0000-0003-2426-3916
Institute of Nuclear Physics, Polish Academy of Sciences · PLKielanowski Institute of Animal Physiology and Nutrition · PLMedical University of Białystok · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article is devoted to a novel class of antimicrobial agents: nanocomposites composed of spherical silica and silver ions located at the silica's surface with the assumed distribution. Such materials are in high demand due to the increasing threat from bacterial strains that are becoming resistant to currently known antibiotics. In particular, we focus on materials that make it possible to limit the growth of bacterial colonies on a variety of tactile surfaces. In this paper, we present a method for preparing a silica-based nanocomposite containing silver ions and the analysis of their antimicrobial properties. Our research revealed that the presence of tested nanocomposite induces very high oxidative stress in the bacteria cell, damaging and modifying bacterial DNA, creating oxidized guanines, cytosines, or adenines, which causes its very rapid destruction, leading to cell death.

Indexed as

Anti-Infective AgentsMetal NanoparticlesNanocompositesAnti-Bacterial AgentsBacteriaMicrobial Sensitivity TestsSilicon DioxideSilverAnti-Bacterial AgentsAnti-Infective AgentsSilicon DioxideSilverantibioticsbacterial E. coli strainsFpg glycosylasefunctional materialsLPSnanocompositesoxidative stressspherical silica

Identifiers

PMID36613985
PMCPMC9820474
OpenAlexW4313327602

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.