Evidence map›Paper›PMID 36615705›Full record

ReviewNutrients2022

Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases.

Monika Fekete, Zsofia Szarvas, Vince Fazekas-Pongor, Agnes Feher, Tamas Csipo, Judit Forrai, Norbert Dosa, Anna Peterfi, Andrea Lehoczki, Stefano Tarantini and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 8 pooled it
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 8 syntheses or guidelines pooled it, 113 citations in OpenAlex.

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  3. Association between life satisfaction and health behaviours among older adults: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2026
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Monika FeketeDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0001-8632-2120
Zsofia SzarvasDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-0022-5053
Vince Fazekas-PongorDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.
Agnes FeherDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.
Tamas CsipoDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0003-2639-2404
Judit ForraiDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.
Norbert DosaDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.
Anna PeterfiDepartment of Public Health, Faculty of Medicine, Semmelweis University, 1089 Budapest, Hungary.
Andrea LehoczkiDepartment of Haematology and Stem Cell Transplantation, National Institute for Haematology and Infectious Diseases, South Pest Central Hospital, 1097 Budapest, Hungary.
Stefano TarantiniDepartment of Neurosurgery, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.ORCID 0000-0001-5627-1430
Janos Tamas VargaDepartment of Pulmonology, Semmelweis University, 1083 Budapest, Hungary.ORCID 0000-0002-8552-1336
Semmelweis University · HUNational Center for Epidemiology · HUOklahoma State University Oklahoma City · US

Funding

Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementiaR03AG070479 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Stefano Tarantini · 2022 to 2022
$290k
Midlife Obesity, Neurovascular Senescence and Cognitive DeclineK01AG073614 · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2025 to 2025
$120k
NIA NIH HHS K01 AG073614NIA NIH HHS R03 AG070479
6 · The paper itself

Abstract

backgroundAn increasing number of studies suggest that diet plays an important role in regulating aging processes and modulates the development of the most important age-related diseases.

objectiveThe aim of this review is to provide an overview of the relationship between nutrition and critical age-associated diseases.

methodsA literature review was conducted to survey recent pre-clinical and clinical findings related to the role of nutritional factors in modulation of fundamental cellular and molecular mechanisms of aging and their role in prevention of the genesis of the diseases of aging.

resultsStudies show that the development of cardiovascular and cerebrovascular diseases, neurodegenerative diseases, cognitive impairment and dementia can be slowed down or prevented by certain diets with anti-aging action. The protective effects of diets, at least in part, may be mediated by their beneficial macro- (protein, fat, carbohydrate) and micronutrient (vitamins, minerals) composition.

conclusionsCertain diets, such as the Mediterranean diet, may play a significant role in healthy aging by preventing the onset of certain diseases and by improving the aging process itself. This latter can be strengthened by incorporating fasting elements into the diet. As dietary recommendations change with age, this should be taken into consideration as well, when developing a diet tailored to the needs of elderly individuals. Future and ongoing clinical studies on complex anti-aging dietary interventions translating the results of preclinical investigations are expected to lead to novel nutritional guidelines for older adults in the near future.

Indexed as

Diet, MediterraneanHealthy AgingAgedAgingBrainDietHumansVitaminsVitaminsaginggeriatric diseaseshealthy agingnutritionprevention

Identifiers

PMID36615705
PMCPMC9824801
OpenAlexW4313590901

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.