Evidence map›Paper›PMID 36615804›Full record

Trial reportNutrients2022

Effects of a Novel Infant Formula on Weight Gain, Body Composition, Safety and Tolerability to Infants: The INNOVA 2020 Study.

Julio Plaza-Diaz, Francisco Javier Ruiz-Ojeda, Javier Morales, Ana Isabel Cristina de la Torre, Antonio García-García, Carlos Nuñez de Prado, Cristóbal Coronel-Rodríguez, Cyntia Crespo, Eduardo Ortega, Esther Martín-Pérez and 9 more

Open access · goldAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Emerging Nonthermal Technologies for the Production of Postbiotics.Comprehensive reviews in food science and food safety · 2025
    Review
  5. Observational
  6. Article
  7. Review
  8. Review
  9. Postbiotics as Metabolites and Their Biotherapeutic Potential.International journal of molecular sciences · 2024
    Review
  10. Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

Julio Plaza-DiazDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-5171-9408
Francisco Javier Ruiz-OjedaDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-4452-0855
Javier MoralesProduct Development Department, Alter Farmacia SA, 28880 Madrid, Spain.
Ana Isabel Cristina de la TorreCS Presentación Sabio, C/Alonso Cano 8, Móstoles, 28933 Madrid, Spain.
Antonio García-GarcíaInstituto Fundación Teófilo Hernando (IFTH), Parque Científico de Madrid, UAM. C/ Faraday 7, Edificio CLAID, 28049 Madrid, Spain.
Carlos Nuñez de PradoConsulta Privada Carlos Núñez, C/Santiago Apóstol 10, Majadahonda, 28220 Madrid, Spain.
Cristóbal Coronel-RodríguezCentro de Salud Amante Laffón, Distrito de Atención Primaria Sevilla, Servicio Andaluz de Salud, 41010 Sevilla, Spain.ORCID 0000-0001-5598-0833
Cyntia CrespoCentro de Salud Amante Laffón, Distrito de Atención Primaria Sevilla, Servicio Andaluz de Salud, 41010 Sevilla, Spain.
Eduardo OrtegaCAP Nova Lloreda, Av. De Catalunya 62-64, 08917 Badalona, Spain.
Esther Martín-PérezCS Parque Loranca, C/de la Alegría 2, Fuenlabrada, 28942 Madrid, Spain.
Fernando FerreiraConsulta Externa Hospital Privado Santa Ángela de la Cruz, Av. De Jerez 59, 41013 Sevilla, Spain.ORCID 0000-0002-5678-740X
Gema García-RonCS La Rivota, C/de las Palmeras s/n, Alcorcón, 28922 Madrid, Spain.ORCID 0000-0002-9775-0451
Ignacio GaliciaInstituto Fundación Teófilo Hernando (IFTH), Parque Científico de Madrid, UAM. C/ Faraday 7, Edificio CLAID, 28049 Madrid, Spain.
María Teresa Santos-García-CuéllarInstituto Fundación Teófilo Hernando (IFTH), Parque Científico de Madrid, UAM. C/ Faraday 7, Edificio CLAID, 28049 Madrid, Spain.
Marcos MarotoInstituto Fundación Teófilo Hernando (IFTH), Parque Científico de Madrid, UAM. C/ Faraday 7, Edificio CLAID, 28049 Madrid, Spain.
Paola RuizCS Las Américas, Av. De América 6, Parla, 28983 Madrid, Spain.
Raquel Martín-MolinaCS Doctor Luengo Rodríguez, C/Nueva York 16, Móstoles, 28938 Madrid, Spain.
Susana Viver-GómezCS Valle de la Oliva, C/Enrique Granados 2, Majadahonda, 28222 Madrid, Spain.ORCID 0000-0002-1582-7735
Angel GilDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-7663-0939
Universidad Autónoma de Madrid · ESUniversidad de Granada · ESAndalusian Health Service · ESTécnicas Reunidas (Spain) · ES

Funding

Alter Farmacia S.A. INNOVA2020
6 · The paper itself

Abstract

Exclusive breastfeeding is recommended for the first six months of life to promote adequate infant growth and development, and to reduce infant morbidity and mortality. However, whenever some mothers are not able to breastfeed their infants, infant formulas mimicking human milk are needed, and the safety and efficacy of each formula should be tested. Here, we report the results of a multicenter, randomized, blinded, controlled clinical trial that aimed to evaluate a novel starting formula on weight gain and body composition of infants up to 6 and 12 months, as well as safety and tolerability. For the intervention period, infants were divided into three groups: group 1 received formula 1 (Nutribén

Indexed as

Infant FormulaBody CompositionBottle FeedingBreast FeedingChildFemaleHumansInfantWeight Gainarachidonic acidBifidobacterium animalis subsp. lactisbody compositionBPL1TMdocosahexaenoic acidinfant formulapostbioticsproteinsafetyα-lactalbumin

Identifiers

PMID36615804
PMCPMC9823847
OpenAlexW4313238024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.