Evidence map›Paper›PMID 36618344›Full record

ArticleFrontiers in immunology2022

IκB

Sarah Frentzel, Andreas Jeron, Alexander Pausder, Olivia Kershaw, Julia Volckmar, Ingo Schmitz, Dunja Bruder

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Regulation and Function of the Atypical IκBs-Bcl-3, IκBEuropean journal of immunology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sarah FrentzelImmune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Andreas JeronImmune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Alexander PausderImmune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Olivia KershawDepartment of Veterinary Medicine, Institute of Veterinary Pathology, Free University Berlin, Berlin, Germany.
Julia VolckmarImmune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Ingo SchmitzDept. of Molecular Immunology, Ruhr University Bochum, Bochum, Germany.
Dunja BruderImmune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Otto-von-Guericke University Magdeburg · DEHelmholtz Centre for Infection Research · DEFreie Universität Berlin · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IκB proteins regulate the inhibition and activation of NF-κB transcription factor complexes. While classical IκB proteins keep NF-κB complexes inactive in the cytoplasm, atypical IκB proteins act on activated NF-κB complexes located in the nucleus. Most of the knowledge regarding the function of IκB proteins has been collected

Indexed as

Listeria monocytogenesListeriosisAnimalsI-kappa B ProteinsImmunity, InnateInflammationMiceNF-kappa BI-kappa B ProteinsNF-kappa Bhyper-inflammationinnate immunityin vivo infectionIκBNSListeria monocytogenesmyeloid cells

Identifiers

PMID36618344
PMCPMC9813228
OpenAlexW4312186672

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.