Evidence map›Paper›PMID 36618364›Full record

ArticleFrontiers in immunology2022

CCR7/dendritic cell axis mediates early bacterial dissemination in

Yuejin Liang, Hui Wang, Casey Gonzales, Joseph Thiriot, Piyanate Sunyakumthorn, Peter C Melby, Jiaren Sun, Lynn Soong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yuejin LiangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Hui WangInstitute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, United States.
Casey GonzalesDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Joseph ThiriotDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Piyanate SunyakumthornDepartment of Veterinary Medicine, United States Army Medical Directorate, Armed Forces Research Institute of Medical Sciences (USAMD-AFRIMS), Bangkok, Thailand.
Peter C MelbyDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Jiaren SunDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Lynn SoongDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · USUnited States Army · US

Funding

EMERGING AND TROPICAL INFECTIOUS DISEASEST32AI007526 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SOONG, LYNN · 1997 to 2025
$3.1M
Biodefense Training ProgramT32AI060549 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ASHOK K CHOPRA, Janice J Endsley · 2004 to 2026
$3.0M
Pathogenic Mechanisms of Vascular Dysfunction in Scrub TyphusR01AI132674 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Yuejin Liang, LYNN SOONG · 2018 to 2026
$3.0M
Neutrophil-Mediated Bacterial Dissemination and Host Immunopathogenesis in a Murine Scrub Typhus ModelR21AI153586 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI LIANG, YUEJIN · 2020 to 2021
$435k
Mincle and STING Activation in Proinflammatory Responses to Orientia InfectionR21AI156536 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOONG, LYNN · 2021 to 2022
$435k
T-Cell Quality and Protective Immunity in a Murine Scrub Typhus ModelR21AI126343 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOONG, LYNN · 2016 to 2017
$426k
NIAID NIH HHS R01 AI132674NIAID NIH HHS R21 AI126343NIAID NIH HHS R21 AI153586NIAID NIH HHS R21 AI156536NIAID NIH HHS T32 AI007526NIAID NIH HHS T32 AI060549
6 · The paper itself

Abstract

Scrub typhus is a life-threatening zoonosis caused by the obligate intracellular bacterium

Indexed as

Orientia tsutsugamushiScrub TyphusAnimalsDendritic CellsDisease Models, AnimalMiceReceptors, CCR7Ccr7 protein, mouseReceptors, CCR7bacterial disseminationCCR7dendritic cellsdraining lymph nodeneutrophilsOrientia tsutaugmsushiscrub tyhusskin

Identifiers

PMID36618364
PMCPMC9813216
OpenAlexW4312187774

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.