Evidence map›Paper›PMID 36625086›Full record

ArticlePharmaceutical biology2023

Antihyperglycemic effects of

Arman Syah Goli, Vilasinee Hirunpanich Sato, Hitoshi Sato, Savita Chewchinda, Jiraporn Leanpolchareanchai, Jannarin Nontakham, Jantana Yahuafai, Thavaree Thilavech, Pongsatorn Meesawatsom, Metawee Maitree

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Antidiabetic Effect ofScientifica · 2026
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  3. Detoxification of paraoxon-ethyl byPharmaceutical biology · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Arman Syah GoliDepartment of Pharmacology, Faculty of Pharmacy, Mahidol University, Thailand.
Vilasinee Hirunpanich SatoDepartment of Pharmacology, Faculty of Pharmacy, Mahidol University, Thailand.ORCID 0000-0002-5837-0739
Hitoshi SatoDivision of Pharmacokinetics and Pharmacodynamics, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Japan.
Savita ChewchindaDepartment of Food Chemistry, Faculty of Pharmacy, Mahidol University, Thailand.
Jiraporn LeanpolchareanchaiDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, Thailand.
Jannarin NontakhamDepartment of Pharmacology, Faculty of Pharmacy, Mahidol University, Thailand.
Jantana YahuafaiClinical Research Section, Division of Research and Academic Support, National Cancer Institute, Bangkok, Thailand.
Thavaree ThilavechDepartment of Food Chemistry, Faculty of Pharmacy, Mahidol University, Thailand.
Pongsatorn MeesawatsomDepartment of Pharmacology, Faculty of Pharmacy, Mahidol University, Thailand.
Metawee MaitreeDepartment of Food Chemistry, Faculty of Pharmacy, Mahidol University, Thailand.
Mahidol University · THNational Cancer Institute of Thailand · THShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveThis study demonstrates the antidiabetic and antioxidant effects of aqueous extract of LS leaves MATERIALS AND

methodsThe effects of aqueous LS leaf extract on glucose uptake, sodium-dependent glucose cotransporter 1 (SGLT1) and glucose transporter 2 (GLUT2) mRNA expression in Caco-2 cells, α-glucosidase, and lipid peroxidation were evaluated

resultsThe extract significantly inhibited glucose uptake (IC

conclusionThe LS extract has potent antihyperglycemic activity to be used as alternative medicine to treat diabetes mellitus.

Indexed as

alpha-GlucosidasesDiabetes Mellitus, ExperimentalAnimalsBlood GlucoseCaco-2 CellsHumansHypoglycemic AgentsMiceNiacinamidePlant ExtractsRNA, MessengerStreptozocinalpha-GlucosidasesBlood GlucoseHypoglycemic AgentsNiacinamidePlant ExtractsRNA, MessengerStreptozocinglucose uptakeGLUT4oral glucose tolerance testα-glucosidase

Identifiers

PMID36625086
PMCPMC9848344
OpenAlexW4315436580

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.