Evidence map›Paper›PMID 36626317›Full record

ArticleAge and ageing2023

Is dynapenic abdominal obesity a risk factor for cardiovascular mortality? A competing risk analysis.

Paula Camila Ramírez, Dayane Capra de Oliveira, Roberta de Oliveira Máximo, Aline Fernanda de Souza, Mariane Marques Luiz, Maicon Luís Bicigo Delinocente, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre

Registry-linked trialAbstract read
In one paragraph

Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07180485 (The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07180485 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity

TypeinterventionalSponsorDalin Tzu Chi General HospitalRan2025 to 2027Enrolled120ConditionsDynapenia, Abdominal ObesityArmswhole body vibration training, control group
3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paula Camila RamírezPrograma de Pós-Graduação em Fisioterapia, Universidade Federal de São Carlos, São Carlos, Brazil.
Dayane Capra de OliveiraPrograma de Pós-Graduação em Fisioterapia, Universidade Federal de São Carlos, São Carlos, Brazil.
Roberta de Oliveira MáximoPrograma de Pós-Graduação em Fisioterapia, Universidade Federal de São Carlos, São Carlos, Brazil.
Aline Fernanda de SouzaPrograma de Pós-Graduação em Fisioterapia, Universidade Federal de São Carlos, São Carlos, Brazil.
Mariane Marques LuizPrograma de Pós-Graduação em Fisioterapia, Universidade Federal de São Carlos, São Carlos, Brazil.
Maicon Luís Bicigo DelinocentePrograma de Pós-Graduação em Gerontologia, Universidade Federal de São Carlos, São Carlos, Brazil.
Andrew SteptoeDepartment of Epidemiology & Public Health, University College London, London, UK.ORCID 0000-0001-7808-4943
Cesar de OliveiraDepartment of Epidemiology & Public Health, University College London, London, UK.
Tiago da Silva AlexandrePrograma de Pós-Graduação em Fisioterapia, Universidade Federal de São Carlos, São Carlos, Brazil.ORCID 0000-0003-3791-9793

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
NIA NIH HHS R01 AG017644
6 · The paper itself

Abstract

backgroundDynapenic abdominal obesity has been shown as a risk factor for all-cause mortality in older adults. However, there is no evidence on the association between this condition and cardiovascular mortality.

objectiveWe aimed to investigate whether dynapenic abdominal obesity is associated with cardiovascular mortality in individuals aged 50 and older.

methodsA longitudinal study with an 8-year follow-up was conducted involving 7,030 participants of the English Longitudinal Study of Ageing study. Abdominal obesity and dynapenia were respectively defined based on waist circumference (> 102 cm for men and > 88 cm for women) and grip strength (< 26 kg for men and < 16 kg for women). The sample was divided into four groups: non-dynapenic/non-abdominal obesity (ND/NAO), non-dynapenic/abdominal obesity (ND/AO), dynapenic/non-abdominal obesity (D/NAO) and dynapenic/abdominal obesity (D/AO). The outcome was cardiovascular mortality. The Fine-Grey regression model was used to estimate the risk of cardiovascular mortality as a function of abdominal obesity and dynapenia status in the presence of competing events controlled by socio-demographic, behavioural and clinical variables.

resultsThe risk of cardiovascular mortality was significantly higher in individuals with D/AO compared with ND/NAO (SHR 1.85; 95% CI: 1.15-2.97). D/NAO was also associated with cardiovascular mortality (SHR: 1.62; 95% CI: 1.08-2.44).

conclusionDynapenic abdominal obesity is associated with cardiovascular mortality, with a larger effect size compared to dynapenia alone in individuals older than 50 years. Thus, prevention strategies and clinical interventions that enable mitigating the harmful effects of these conditions should be adopted to diminish such risk.

Indexed as

Cardiovascular DiseasesObesityAgedFemaleHand StrengthHumansLongitudinal StudiesMaleMiddle AgedObesity, AbdominalRisk AssessmentRisk Factorsabdominal obesitycardiovascular diseasedynapeniaEnglish Longitudinal Study of Ageing (ELSA) studymortalityolder people

Identifiers

PMID36626317
PMCPMC9831270

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.