Evidence mapPaperPMID 36627697Full record

ArticleBMC endocrine disorders2023

Unique genetic variants of lean nonalcoholic fatty liver disease: a retrospective cohort study.

Jie Li, Na Wu, Yukun Yang, Xiangyu Zhai, Fan Yuan, Fengwei Zhang, Ning Yu, Dong Li, Ruirui Wang, Jianying Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC endocrine disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Mediating role of insulin resistance in the relationship between hypertension and NAFLD and construction of its risk prediction model].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jie Li *Shanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Na Wu *Shanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yukun Yang *Changhai Hospital, Naval Military Medical University, Shanghai, China.
Xiangyu ZhaiGraduate School of Sport Sciences, Waseda University, Saitama, Japan.
Fan YuanBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, Shanghai, China.
Fengwei ZhangShanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ning YuShanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Dong LiZhangjiang Community Health Service Center of Pudong New District, Shanghai, China.
Ruirui WangShanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jianying WangShanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lei ZhangShanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yi ShiBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, Shanghai, China.
Guang HeBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, Shanghai, China. heguangbiox@163.com.
Baocheng LiuShanghai Innovation Center of Traditional Chinese Medicine Health Service, School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China. baochliu_lab@163.com.
Shanghai University of Traditional Chinese Medicine · CNShanghai Jiao Tong University · CNSecond Military Medical University · CNWaseda University · JP

Funding

Local Colleges Faculty Constitution of Shanghai MSTC 2022 22010504300National Natural Science Foundation of China 81973730Shanghai Collaborative Innovation Center for Chronic Disease Prevention and Health Services 2021 Science and Technology 02-37Three-year action plan for Shanghai ZY (2021-2023)-0211
6 · The paper itself

Abstract

We investigated the prevalence and clinical metabolic characteristics of lean nonalcoholic fatty liver disease (NAFLD) in an elderly Chinese population and assessed the relevance of lipid markers and genetic variation. All 5,338 community subjects underwent detailed clinical and laboratory examinations and were divided into three groups: lean (Body mass index (BMI) < 23 kg/m

Indexed as

Non-alcoholic Fatty Liver DiseaseAgedAlpha-Ketoglutarate-Dependent Dioxygenase FTOBody Mass IndexGenome-Wide Association StudyHumansObesityPolymorphism, Single NucleotideRetrospective StudiesAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanFTOGCKRGenetic riskLean NAFLDLow-density lipoprotein

Identifiers

PMID36627697
PMCPMC9830772
OpenAlexW4315491758

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.