Evidence map›Paper›PMID 36628002›Full record

ReviewCureus2022

The Anti-Depressant Effects of Statins in Patients With Major Depression Post-Myocardial Infarction: An Updated Review 2022.

Sai Dheeraj Gutlapalli, Hadi Farhat, Huma Irfan, Kanmani Muthiah, Namratha Pallipamu, Sogand Taheri, Suvedha S Thiagaraj, Twisha S Shukla, Sheiniz Giva, Sai Sri Penumetcha

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Depression Following Acute Coronary Syndrome: A Review.Reviews in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sai Dheeraj GutlapalliInternal Medicine Clinical Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Hadi FarhatCardiology, Rheumatology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Huma IrfanResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Kanmani MuthiahNeurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Namratha PallipamuInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sogand TaheriMedical Science, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Suvedha S ThiagarajInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Twisha S ShuklaPediatric, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sheiniz GivaNeonatology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sai Sri PenumetchaGeneral Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · USRichmond University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statins are the most commonly prescribed lipid-lowering agents in patients with cardiovascular disease, and more than half of the patients with cardiovascular disease have associated depressive symptoms, particularly post-myocardial infarction, which is a major trigger for depression. In our research, we tried to understand the anti-depressant effects of statins, the mechanisms, risks and benefits, and potential drug-drug interactions with anti-depressant medications. We reviewed all the relevant information from inception up to September 2022 regarding the anti-depressant effects of statins. The database used was PubMed, and the keywords were statins, major depression, post-myocardial infarction, and hydroxy methylglutaryl-coenzyme A

Indexed as

antidepressant drugappropriate statin usehmg- coa reductase inhibitorsmajor depression disorderpost-myocardial infarctionstatin safetystatin use

Identifiers

PMID36628002
PMCPMC9825119
OpenAlexW4311877493

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.