Evidence mapPaperPMID 36636367Full record

ArticleMedComm2023

Loss of CRY2 promotes regenerative myogenesis by enhancing PAX7 expression and satellite cell proliferation.

Yingxue Hao, Ting Xue, Song-Bai Liu, Sha Geng, Xinghong Shi, Panting Qian, Wei He, Jiqing Zheng, Yanfang Li, Jing Lou and 6 more

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Co-expression network analysis reveals repression ofbioRxiv : the preprint server for biology · 2026
    Article
  2. New insights into the skeletal muscle circadian clock in ruminants.Journal of animal science and biotechnology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Deletion of TECRL promotes skeletal muscle repair by up-regulating EGR2.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Yingxue HaoCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.ORCID https://orcid.org/0000-0001-7996-6534
Ting XueCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Song-Bai LiuSuzhou Vocational Health College, Suzhou Key Laboratory of Biotechnology for Laboratory Medicine Suzhou Jiangsu P. R. China.
Sha GengCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Xinghong ShiCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Panting QianCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Wei HeCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Jiqing ZhengCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Yanfang LiCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Jing LouCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Tianze ShiCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Ge WangCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Xiaoxiao WangSuzhou Vocational Health College, Suzhou Key Laboratory of Biotechnology for Laboratory Medicine Suzhou Jiangsu P. R. China.
Yanli WangInstitute for Cardiovascular Science and Department of Cardiovascular Surgery First Affiliated Hospital and Medical College of Soochow University Suzhou Jiangsu P. R. China.
Yangxin LiInstitute for Cardiovascular Science and Department of Cardiovascular Surgery First Affiliated Hospital and Medical College of Soochow University Suzhou Jiangsu P. R. China.
Yao-Hua SongCyrus Tang Hematology Center Collaborative Innovation Center of Hematology Soochow University Suzhou P. R. China.
Soochow University · CNShanxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regenerative capacity of skeletal muscle is dependent on satellite cells. The circadian clock regulates the maintenance and function of satellite cells. Cryptochrome 2 (CRY2) is a critical component of the circadian clock, and its role in skeletal muscle regeneration remains controversial. Using the skeletal muscle lineage and satellite cell-specific CRY2 knockout mice (CRY2

Indexed as

CRY2muscle regenerationsatellite cells

Identifiers

PMID36636367
PMCPMC9830134
OpenAlexW4315927816

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.