Evidence map›Paper›PMID 36638804›Full record

ReviewNeuron2023

THC and CBD: Similarities and differences between siblings.

Nephi Stella

Open access · greenAbstract readReview
In one paragraph

Review in Neuron, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 3 pooled it
29.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, crossover study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Trial
  6. Review
  7. Review
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. The psychoactive cannabinoid THC inhibits peripheral nociceptors by targeting NaNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Nephi StellaDepartment of Pharmacology, Department Psychiatry and Behavioral Sciences, Center for Cannabis Research, Center for the Neurobiology of Addiction, Pain, and Emotion, University of Washington School of Medicine, Seattle, WA 98195, USA.
University of Washington · US

Funding

Impact on adult mouse brain of oral THC and CBD consumption during adolescenceR21DA051558 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2020 to 2021
$428k
Differential control of 2-AG’s activity at CB1R by ABHD6 and MAGLR21DA056816 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2023 to 2024
$428k
Role of CB1R expressed in the prefrontal cortex in the control of locomotionR21DA057186 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2023 to 2024
$428k
Molecular mechanism of ABHD6 enzymatic activity in neuronsR21NS118130 · NINDS · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2020 to 2020
$428k
ABHD6 and amphetamine stimulated locomotionR21DA047626 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI, ZWEIFEL, LARRY S · 2019 to 2020
$409k
NIDA NIH HHS R21 DA047626NIDA NIH HHS R21 DA051558NIDA NIH HHS R21 DA056816NIDA NIH HHS R21 DA057186NINDS NIH HHS R21 NS118130
6 · The paper itself

Abstract

Δ

Indexed as

CannabidiolCannabinoidsCannabinoid Receptor AgonistsDronabinolHumansSiblingsCannabidiolCannabinoid Receptor AgonistsCannabinoidsDronabinol

Identifiers

PMID36638804
PMCPMC9898277
OpenAlexW4315705350

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.