ArticleJournal of diabetes2023
Changes in fasting blood glucose status and incidence of cardiovascular disease: The China-PAR project.
Article in Journal of diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Yoga interventions and randomized controlled trials: key issues and the centered impact on sedentary lifestyle-associated cardiometabolic disorders.Frontiers in clinical diabetes and healthcare · 2026Pooled it
- Global Trends in the Burden of Ischemic Stroke Attributable to Diabetes Versus Atrial Fibrillation.Stroke · 2026Article
- Fasting blood glucose trajectories and atherosclerosis risk: a longitudinal cohort study with threshold analysis in Chongqing, China.Journal of health, population, and nutrition · 2026Article
- Burden and causes due to high fasting plasma glucose in China from 1990 to 2021: a systematic analysis and comparison with the global burden.BMC public health · 2026Article
- Nationwide prospective cohort study in China: the impact of cumulative modified cardiometabolic index on cardiovascular disease incidence.Frontiers in cardiovascular medicine · 2026Article
- Triglyceride-glucose index combined with body roundness index predicts cardiovascular risk in middle-aged and elderly individuals: a 10-year cohort study.Scientific reports · 2025Article
- Relative effectiveness of different exercise interventions on cardiovascular events in individuals with prediabetes: a systematic review and network meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Short leukocyte telomere length and high plasma phospholipid fatty acids increase the risk of type 2 diabetes.Endocrine connections · 2024Article
- Fasting blood glucose level and risk of all-cause and cause-specific mortality in peritoneal dialysis patients.Journal of diabetes · 2024Article
- Untangling pathways of risk factors associated with hypertension among dysglycemia adults in eastern China: a structural equation model approach.Acta diabetologica · 2024Article
- The associations of risk of cardiovascular disease with development stages of diabetes in Chinese population: findings from a retrospective cohort study in QuZhou city.BMC endocrine disorders · 2024Article
- Metabolic Effects of Anti-TNF-α Treatment in Rheumatoid Arthritis.Diseases (Basel, Switzerland) · 2023Article
- Identifying Cardiovascular Disease Risk Factors in Adults with Explainable Artificial Intelligence.Anatolian journal of cardiology · 2023Article
- Changes in fasting blood glucose status and incidence of cardiovascular disease: The China-PAR project.Journal of diabetes · 2023Article
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Authors and funding
19 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundThe effect of long-standing prediabetes or its transition on incident cardiovascular disease (CVD) is unclear. This study aimed to evaluate the association of changes in fasting blood glucose (FBG) status with the risk of developing CVD.
methodsThis research included 12 145 Chinese adults aged 35-74 years and free from diabetes mellitus (DM) at baseline. Study participants were cross-classified into six categories according to glucose at the first (1998-2001) and the second visit after 8 years: normal fasting glucose (NFG; 50-99 mg/dl), impaired FBG (IFG; 100-125 mg/dl), and DM. Cox proportional hazard regression model was used to estimate the hazard ratio (HR) and 95% confidence interval (CI) for CVD associated with transition of glucose status.
resultsDuring a median follow-up of 5.5 years, 373 incident CVD cases occurred. Compared with participants remaining persistent NFG, a higher risk of developing CVD was identified among those remaining persistent IFG, progressing to DM from NFG or from IFG, with the multivariate-adjusted HR (95% CI) of 1.792 (1.141, 2.816), 1.723 (1.122, 2.645) and 1.946 (1.120, 3.381), respectively. Furthermore, when stratified by glucose status at baseline, persistent IFG and progression from IFG to DM still increased CVD risk in comparison with reversion from IFG to NFG, with the multivariate-adjusted HR (95% CI) of 1.594 (1.003, 2.532) and 1.913 (1.080, 3.389).
conclusionsParticipants with long-standing IFG and progressing to DM had a higher risk of developing CVD. Further well-designed studies are warranted to assess the association of other phenotypes or prediabetes duration with CVD.
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