Evidence map›Paper›PMID 36639792›Full record

ReviewFluids and barriers of the CNS2023

Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus".

Jason K Karimy, Jessie C Newville, Cameron Sadegh, Jill A Morris, Edwin S Monuki, David D Limbrick, James P McAllister Ii, Jenna E Koschnitzky, Maria K Lehtinen, Lauren L Jantzie

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Fluids and barriers of the CNS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats.Journal of visualized experiments : JoVE · 2025
    Article
  3. Review
  4. Mechanisms of hydrocephalus after intraventricular haemorrhage: a review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 1 country.

Jason K KarimyDepartment of Family Medicine, Mountain Area Health Education Center - Boone, North Carolina, 28607, USA.
Jessie C NewvilleDepartment of Pediatrics and Neurosurgery, Johns Hopkins Children's Center, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
Cameron SadeghDepartment of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, MA, Boston, 02114, USA.
Jill A MorrisNational Institute of Neurological Disorders and Stroke, Neuroscience Center, National Institutes of Health, 6001 Executive Blvd, NSC Rm 2112, Bethesda, MD, 20892, USA.
Edwin S MonukiDepartments of Pathology & Laboratory Medicine and Developmental & Cell Biology, University of California Irvine, Irvine, CA, 92697, USA.
David D LimbrickDepartments of Neurosurgery and Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA.
James P McAllister IiDepartments of Neurosurgery and Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA.
Jenna E KoschnitzkyHydrocephalus Association, Bethesda, MD, 20814, USA.
Maria K LehtinenDepartment of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA. Maria.Lehtinen@childrens.harvard.edu.
Lauren L JantzieDepartment of Pediatrics and Neurosurgery, Johns Hopkins Children's Center, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA. LJantzie@jhmi.edu.
Washington University in St. Louis · USBoston Children's Hospital · USHydrocephalus Association · USJohns Hopkins Children's Center · USKennedy Krieger Institute · USMassachusetts General Hospital · USMountain Area Health Education Center · USNational Institutes of Health · USUniversity of California, Irvine · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Reducing infections and blockage associated with long-term implantation of ventriculoperitoneal and related shuntsR44NS139774 · NINDS · WYNNVISION, LLC · PI HARRIS, CAROLYN A, MCALLISTER, JAMES PATTERSON · 2025 to 2025
$306k
NICHD NIH HHS P50 HD105351NINDS NIH HHS R44 NS139774
6 · The paper itself

Abstract

The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientists conducting research on multiple hydrocephalus etiologies with select outside researchers. The main goals of the workshop were to explore areas of potential overlap between hydrocephalus etiologies and identify drug targets that could positively impact various forms of hydrocephalus. This report details the major themes of the workshop and the research presented on three cell types that are targets for new hydrocephalus interventions: choroid plexus epithelial cells, ventricular ependymal cells, and immune cells (macrophages and microglia).

Indexed as

Cerebral HemorrhageHydrocephalusChoroid PlexusHumansCerebrospinal fluidCiliaEpendymaGerminal matrix hemorrhageHydrocephalusIntraventricular hemorrhagePosthemorrhagicPost-infectious

Identifiers

PMID36639792
PMCPMC9838022
OpenAlexW4315865948

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.