Evidence map›Paper›PMID 36640316›Full record

ArticleCell reports2023

Synaptotagmin-1 is a Ca

Joseph J Lebowitz, Aditi Banerjee, Claire Qiao, James R Bunzow, John T Williams, Pascal S Kaeser

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. The Synaptic Vesicle Priming Protein Munc13 Mediates Evoked Somatodendritic Dopamine Release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joseph J LebowitzVollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.
Aditi BanerjeeDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Claire QiaoDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
James R BunzowVollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.
John T WilliamsVollum Institute, Oregon Health and Science University, Portland, OR 97239, USA. Electronic address: williamj@ohsu.edu.
Pascal S KaeserDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: kaeser@hms.harvard.edu.
Harvard University · USOregon Health & Science University · US

Funding

BIOLOGICAL BASES OF DRUG-SEEKING BEHAVIORT32DA007262 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 1991 to 2022
$9.4M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
COCAINE: EFFECTS ON SINGLE NEURONSR01DA004523 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 1987 to 2025
$7.6M
Molecular Dissection of Active Zone Functions in Neurotransmitter ReleaseR01NS083898 · NINDS · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2014 to 2026
$5.9M
Architecture and Function of Striatal Dopamine Signaling MachineryR01NS103484 · NINDS · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2017 to 2026
$4.7M
NICHD NIH HHS P50 HD105351NIDA NIH HHS R01 DA004523NIDA NIH HHS T32 DA007262NINDS NIH HHS R01 NS083898NINDS NIH HHS R01 NS103484
6 · The paper itself

Abstract

Modes of somatodendritic transmission range from rapid synaptic signaling to protracted regulation over distance. Somatodendritic dopamine secretion in the midbrain leads to D2 receptor-induced modulation of dopamine neurons on the timescale of seconds. Temporally imprecise release mechanisms are often presumed to be at play, and previous work indeed suggested roles for slow Ca

Indexed as

DopamineSynaptic TransmissionAnimalsCalciumCell CommunicationDopaminergic NeuronsExocytosisMiceCalciumDopaminecalcium sensorCP: Neurosciencedopamineexocytosisneurotransmissionsecretionsomatodendritic releasesynaptotagmin

Identifiers

PMID36640316
PMCPMC9993464
OpenAlexW4313368345

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.