Evidence map›Paper›PMID 36640340›Full record

ArticleCell reports2023

The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8

Joseph W Dean, Eric Y Helm, Zheng Fu, Lifeng Xiong, Na Sun, Kristen N Oliff, Marcus Muehlbauer, Dorina Avram, Liang Zhou

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Evolving role of CD8Frontiers in immunology · 2026
    Review
  15. Review
  16. Increased CD103Cancer immunology, immunotherapy : CII · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. CD103Nature communications · 2025
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Joseph W DeanDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Eric Y HelmDepartment of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville, FL 32608, USA.
Zheng FuDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Lifeng XiongDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Na SunDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Kristen N OliffDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.
Marcus MuehlbauerDivision of Gastroenterology, Hepatology and Nutrition, College of Medicine, University of Florida, Gainesville, FL 32608, USA.
Dorina AvramDepartment of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Liang ZhouDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA. Electronic address: liangzhou497@ufl.edu.
University of Florida · USMoffitt Cancer Center · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Role of Bcl11b in CD4+ T cells and innate lymphoid cellsR01AI067846 · NIAID · UNIVERSITY OF FLORIDA · PI AVRAM, DORINA · 2007 to 2023
$6.2M
Regulation of Gut Innate Lymphoid Cells by AhrR01AI132391 · NIAID · UNIVERSITY OF FLORIDA · PI Liang Zhou · 2017 to 2026
$4.8M
BASIC MICROBIOLOGY &INFECTIOUS DISEASEST32AI007110 · NIAID · UNIVERSITY OF FLORIDA · PI Stephanie M Karst · 1985 to 2026
$4.3M
Role of RORgt+ (note: g: is gamma symbol) lymphocytes in Gut Tissue HomeostasisR01AI157109 · NIAID · UNIVERSITY OF FLORIDA · PI ZHOU, LIANG · 2021 to 2025
$2.8M
AhR activation in Th17 and Treg cell differentiationR01AI089954 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHOU, LIANG · 2010 to 2014
$1.9M
Sony Cell Sorter SH800 SystemS10OD021676 · OD · UNIVERSITY OF FLORIDA · PI PASCUAL, DAVID W · 2016 to 2016
$296k
NCI NIH HHS P30 CA076292NIAID NIH HHS R01 AI067846NIAID NIH HHS R01 AI089954NIAID NIH HHS R01 AI132391NIAID NIH HHS R01 AI157109NIAID NIH HHS T32 AI007110NIH HHS S10 OD021676
6 · The paper itself

Abstract

The Aryl hydrocarbon receptor (Ahr) regulates the differentiation and function of CD4

Indexed as

CD8-Positive T-LymphocytesImmunologic MemoryAnimalsCell DifferentiationGenome-Wide Association StudyHumansMiceReceptors, Aryl HydrocarbonReceptors, Aryl Hydrocarbonaryl hydrocarbon receptorcancer immunologyCD8(+) T cellCP: Immunologycytotoxicitydevelopmentdifferentiationmucosal immunologytissue resident memorytumor infiltrating lymphocyte

Identifiers

PMID36640340
PMCPMC9940759
OpenAlexW4313491523

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.