ArticleGeriatric nursing (New York, N.Y.)
Self-reported pain and fatigue are associated with physical and cognitive function in middle to older-aged adults.
Article in Geriatric nursing (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- A phenomenological study of fatigue experience in community-dwelling older adults.BMC geriatrics · 2026Article
- Unique contributions of heart failure and chronic pain on physical function and quality of life in older adults.Geriatric nursing (New York, N.Y.) · 2026Article
- Menopause-related brain fog as a midlife window in women's brain aging: toward ecologically valid measurement and digital phenotyping.Frontiers in human neuroscience · 2026Article
- The effects of pulsed electromagnetic field therapy on pain and physical functions in patients with soft tissue injuries: a systematic review of randomised controlled trials.Frontiers in sports and active living · 2026Review
- Fatigue as a mediator between multidimensional influencing factors and lower limb function in older adults based on the theory of unpleasant symptoms.BMC geriatrics · 2025Article
- Translational insights into pain mechanisms and balance impairments in aging: a cross-sectional study.Frontiers in aging neuroscience · 2025Article
- Construction and verification of a risk prediction model for cognitive frailty in older patients with chronic obstructive pulmonary disease and diabetes mellitus.The Journal of international medical research · 2024Article
- Relationships between Physical Activity and Selected Chronic Diseases among Functionally Independent Long-Term Care Residents during the Post-Lockdown Period in Croatia.International journal of environmental research and public health · 2023Observational
- Microglia role in the pain phenomenon.Revista da Associacao Medica Brasileira (1992) · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Persistent fatigue is often reported in those with chronic musculoskeletal pain. Separately, both chronic pain and chronic fatigue contribute to physical and cognitive decline in older adults. Concurrent pain and fatigue symptoms may increase disability and diminish quality of life, though little data exist to show this. The purpose of this study was to examine associations between self-reported pain and fatigue, both independently and combined, with cognitive and physical function in middle-older-aged adults with chronic knee pain. Using a cross-sectional study design participants (n = 206, age 58.0 ± 8.3) completed questionnaires on pain and fatigue, a physical performance battery to assess physical function, and the Montreal Cognitive Assessment. Hierarchical regressions and moderation analyses were used to assess the relationship between the variables of interest. Pain and fatigue both predicted physical function (β = -0.305, p < 0.001; β = -0.219, p = 0.003, respectively), however only pain significantly predicted cognitive function (β = -0.295, p <0.001). A centered pain*fatigue interaction was a significant predictor of both cognitive function (β = -0.137, p = 0.049) and physical function (β = -0.146, p = 0.048). These findings indicate that self-reported fatigue may contribute primarily to decline in physical function among individuals with chronic pain, and less so to decline in cognitive function. Future studies should examine the impact of both cognitive and physical function decline together on overall disability and health.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.