Evidence map›Paper›PMID 36643871›Full record

ArticleDyes and pigments : an international journal2023

Single-molecule characterization of a bright and photostable deep-red fluorescent squaraine-figure-eight (SF8) dye.

Kirill Kniazev, Tianle Guo, Canjia Zhai, Rananjaya S Gamage, Sushrut Ghonge, Pavel A Frantsuzov, Masaru Kuno, Bradley Smith

Abstract read
In one paragraph

Article in Dyes and pigments : an international journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kirill KniazevDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0002-7338-1436
Tianle GuoDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.
Canjia ZhaiDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0002-5348-2790
Rananjaya S GamageDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0003-3960-0276
Sushrut GhongeDepartment of Physics, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0003-4370-3331
Pavel A FrantsuzovVoevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Science, Institutskaya 3, Novosibirsk, 630090, Russia.ORCID 0000-0002-7717-5453
Masaru KunoDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0003-4210-8514
Bradley SmithDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0003-4120-3210

Funding

Molecular Probes for Biomembrane RecognitionR35GM136212 · NIGMS · UNIVERSITY OF NOTRE DAME · PI Bradley D Smith · 2020 to 2026
$2.5M
NIGMS NIH HHS R35 GM136212
6 · The paper itself

Abstract

Squaraine Figure Eight (SF8) dyes are a unique class of deep-red fluorescent dyes with self-threaded molecular architecture that provides structural rigidity while simultaneously encapsulating and protecting the emissive fluorochrome. Previous cell microscopy and bulk phase studies of SF8 dyes indicated order of magnitude enhancements in photostability over conventional pentamethine cyanine dyes such as Cy5. Studies conducted at the single molecule level now reveal that these ensemble level enhancements carry over to the single molecule level in terms of enhanced emission quantum yields, longer times to photobleaching, and enhanced total photon yields. When compared to Cy5, the SF8-based dye SF8(D4)

Indexed as

deep-red fluorescencephoton yieldphotostabilitysingle moleculesquaraine

Identifiers

PMID36643871
PMCPMC9835836

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.