Evidence map›Paper›PMID 36644201›Full record

ArticleAtherosclerosis plus2022

Novel protein-truncating variant in the

Gabriele Mango, Nicola Osti, Silvia Udali, Anna Vareschi, Giovanni Malerba, Alejandro Giorgetti, Francesca Pizzolo, Simonetta Friso, Domenico Girelli, Oliviero Olivieri and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Atherosclerosis plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Gabriele MangoDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Nicola OstiDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Silvia UdaliDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Anna VareschiDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Giovanni MalerbaLaboratory of Computational Genomics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134, Verona, Italy.
Alejandro GiorgettiDepartment of Biotechnology, University of Verona, Verona, 37134, Italy.
Francesca PizzoloDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Simonetta FrisoDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Domenico GirelliDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Oliviero OlivieriDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Annalisa CastagnaDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
Nicola MartinelliDepartment of Medicine, Unit of Internal Medicine, University of Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Genetic testing is still rarely used for the diagnosis of dyslipidemia, even though gene variants determining plasma lipids levels are not uncommon. Methods: Starting from a a pilot-analysis of targeted Next Generation Sequencing (NGS) of 5 genes related to familial hypercholesterolemia ( Results: Conclusions: Our data support the use of targeted NGS in well-characterized clinical settings, as well as they indicate that.a partial block of ApoB production may be well tolerated and improve cardiovascular outcomes.

Indexed as

ApoB, Apolipoprotein BApolipoprotein BCAD, Coronary Artery DiseaseCoronary Artery DiseaseDyslipidemiaNext Generation SequencingNGS, Next Generation Sequencing

Identifiers

PMID36644201
PMCPMC9833228
OpenAlexW4283330968

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.