ArticleJACC. Cardiovascular imaging2023
Incident Clinical and Mortality Associations of Myocardial Native T1 in the UK Biobank.
Article in JACC. Cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Cardiac magnetic resonance T1 mapping predicts outcome in patients with a systemic right ventricle:European heart journal open · 2026Article
- Advancements in Cardiac Magnetic Resonance Imaging: Innovations, Challenges, and Future Directions.Reviews in cardiovascular medicine · 2026Review
- Clinical Phenotypes in Hypertension: A Data-Driven Approach to Risk Stratification.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Myocardial fibrosis and tissue alterations predict cardiovascular outcomes in chronic kidney disease-a prospective virtual twin study design using large-scale population database.Frontiers in cardiovascular medicine · 2026Article
- Burden of diffuse myocardial fibrosis assessed by cardiac magnetic resonance in repaired tetralogy of Fallot: A systematic review and meta-analysis.International journal of cardiology. Congenital heart disease · 2025Article
- Causal relevance of clonal haematopoiesis with cardiac disease and adverse remodelling: a Mendelian randomisation study.Open heart · 2025Article
- Identification, characterisation and outcomes of pre-atrial fibrillation in heart failure with reduced ejection fraction.ESC heart failure · 2025Article
- Cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Observational
- CMR assessment of epicardial edipose tissue in relation to myocardial inflammation and fibrosis in patients with new-onset atrial arrhythmias after STEMI.BMC cardiovascular disorders · 2025Article
- Impact of self-reported SARS-CoV-2 antibody positivity on cardiac structure and function: findings from UK Biobank CMR cohort.Frontiers in cardiovascular medicine · 2025Article
- The Association Between Periodontal Disease and Cardiovascular Disease: Insights From Imaging, Observational, and Genetic Data.JACC. Advances · 2024Article
- Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.European heart journal · 2024Article
- Misclassification of females and males in cardiovascular magnetic resonance parametric mapping: the importance of sex-specific normal ranges for diagnosis of health vs. disease.European heart journal. Cardiovascular Imaging · 2024Article
- Association of Lipoprotein(a) Levels With Myocardial Fibrosis in the Multi-Ethnic Study of Atherosclerosis.Journal of the American College of Cardiology · 2023Article
- Prognostic Significance of Different Ventricular Ectopic Burdens During Submaximal Exercise in Asymptomatic UK Biobank Subjects.Circulation · 2023Article
- Higher HDL cholesterol levels are associated with increased markers of interstitial myocardial fibrosis in the MultiEthnic Study of Atherosclerosis (MESA).Scientific reports · 2023Article
- Phenotyping heart failure by cardiac magnetic resonance imaging of cardiac macro- and microscopic structure: state of the art review.European heart journal. Cardiovascular Imaging · 2023Review
- Characterizing the hypertensive cardiovascular phenotype in the UK Biobank.European heart journal. Cardiovascular Imaging · 2023Article
- Population-Associated Variance in Native Myocardial T1: Value Added or Is There More to Come?JACC. Cardiovascular imaging · 2023Article
- Periodontal Disease Associated With Interstitial Myocardial Fibrosis: The Multiethnic Study of Atherosclerosis.Journal of the American Heart Association · 2023Article
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Abstract
backgroundCardiac magnetic resonance native T1-mapping provides noninvasive, quantitative, and contrast-free myocardial characterization. However, its predictive value in population cohorts has not been studied.
objectivesThe associations of native T1 with incident events were evaluated in 42,308 UK Biobank participants over 3.17 ± 1.53 years of prospective follow-up.
methodsNative T1-mapping was performed in 1 midventricular short-axis slice using the Shortened Modified Look-Locker Inversion recovery technique (WIP780B) in 1.5-T scanners (Siemens Healthcare). Global myocardial T1 was calculated using an automated tool. Associations of T1 with: 1) prevalent risk factors (eg, diabetes, hypertension, and high cholesterol); 2) prevalent and incident diseases (eg, any cardiovascular disease [CVD], any brain disease, valvular heart disease, heart failure, nonischemic cardiomyopathies, cardiac arrhythmias, atrial fibrillation [AF], myocardial infarction, ischemic heart disease [IHD], and stroke); and 3) mortality (eg, all-cause, CVD, and IHD) were examined. Results are reported as odds ratios (ORs) or HRs per SD increment of T1 value with 95% CIs and corrected P values, from logistic and Cox proportional hazards regression models.
resultsHigher myocardial T1 was associated with greater odds of a range of prevalent conditions (eg, any CVD, brain disease, heart failure, nonischemic cardiomyopathies, AF, stroke, and diabetes). The strongest relationships were with heart failure (OR: 1.41 [95% CI: 1.26-1.57]; P = 1.60 × 10
conclusionsThis large population study demonstrates the utility of myocardial native T1-mapping for disease discrimination and outcome prediction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.