ArticleArchives of endocrinology and metabolism2023
The triglyceride-glucose index as an indicator of insulin resistance and cardiometabolic risk in Brazilian adolescents.
Article in Archives of endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effect of exercise intervention on the triglyceride-glucose (TyG) index in adolescents with overweight or obesity: a systematic review and Bayesian dose-response meta-analysis.BMC pediatrics · 2025Pooled it
- Pooled it
- Triglyceride-glucose index, neutrophil-to-lymphocyte ratio, and high-sensitivity C-reactive protein across albuminuria stages in type 2 diabetes.Scientific reports · 2026Article
- Phase angle and triglyceride-glucose index as biomarkers of glycemic control, body composition and cardiovascular risk in adolescents with type 1 diabetes: a cross-sectional study.Journal of endocrinological investigation · 2026Article
- Comparative analysis of hormonal and metabolic indices in phenotypic subgroups of polycystic ovary syndrome.Journal of the Turkish German Gynecological Association · 2026Article
- Article
- The triglyceride glucose index as a biomarker for different glucose disorders in overweight and obese children and adolescents.European journal of pediatrics · 2025Article
- Article
- Association between the combination of the triglyceride-glucose index and obesity-related indices with hyperuricemia among children and adolescents in China.Lipids in health and disease · 2025Article
- Comparison of triglyceride glucose index and other insulin resistance indexes in children with overweight and obesity.BMC endocrine disorders · 2025Article
- Triglyceride-glucose index as a marker in cardiovascular diseases; a bibliometric study and visual analysis.Annals of medicine and surgery (2012) · 2025Review
- Effect of adipose tissue deposition on insulin resistance in middle-aged and elderly women: Based on QCT and MRI mDIXON-Quant.Journal of diabetes investigation · 2025Article
- Association between triglyceride-glucose index and vitamin D levels in Saudi postmenopausal women: a cross-sectional study.International journal of clinical and experimental pathology · 2025Article
- Uric acid and unhealthy metabolic phenotype in Colombian children.Pediatric endocrinology, diabetes, and metabolism · 2025Article
- Relationship between air pollution exposure and insulin resistance in Chinese middle-aged and older populations: evidence from Chinese cohort.Frontiers in public health · 2025Article
- Adolescent PCOS and long-term metabolic risk: insights from triglycerides to high-density lipoprotein cholesterol ratio and high-density lipoprotein cholesterol profiles.Frontiers in endocrinology · 2025Article
- Role of Peripheral and Central Insulin Resistance in Neuropsychiatric Disorders.Journal of clinical medicine · 2024Review
- High free sugars, insulin resistance, and low socioeconomic indicators: the hubs in the complex network of non-communicable diseases in adolescents.Diabetology & metabolic syndrome · 2024Article
- The mediating effect of TyG-related indicators between long-term exposure to particulate matter and cardiovascular disease: evidence from a national longitudinal cohort study.Lipids in health and disease · 2024Article
- Biochemical and Anthropometric Indices of Insulin Resistance in Obese and Overweight Children with Metabolic Dysfunction-Associated Fatty Liver Disease.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To set cutoff points for the triglyceride and glucose index (TyG) as a marker of insulin resistance (IR) for the pediatric population. Subjects and methods: This was a cross-sectional study with schoolchildren population-based data using data of 377 schoolchildren age 10 to 17 years of both sexes. We studied metabolic variables associated with IR indicators, such as fasting insulin and blood glucose, to calculate the homeostatic model assessment (HOMA-IR), and we studied triglycerides (TG) to determine the TyG index. We obtained TyG cutoff values for IR using the receiver operation characteristic (ROC), with definitions of sensitivity (Sen), specificity (Spe), and area under the ROC curve (AUC), with the HOMA-IR as reference. Results: The cutoff points of the TyG index for IR in adolescents are 7.94 for both sexes, 7.91 for boys, and 7.94 for girls, indicating moderate discriminatory power. When we also considered anthropometric variables of excess weight [TyG-BMI (body mass index)] and visceral fat [TyG-WC (waist circumference)], these indexes reached AUC values higher than 0.72, enhancing their potential use for a good diagnosis. Conclusion: TyG has proven to be a useful instrument for identifying IR in adolescent health screening, with high discrimination capacity when added to anthropometric variables, making it a feasible and inexpensive option.
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