Evidence map›Paper›PMID 36651739›Full record

ArticleAntimicrobial agents and chemotherapy2023

Frequent Transmission of Streptococcus pneumoniae Serotype 35B and 35D, Clonal Complex 558 Lineage, across Continents and the Formation of Multiple Clades in Japan.

Koh Shinohara, Takao Fujisawa, Bin Chang, Yutaka Ito, Shigeru Suga, Yasufumi Matsumura, Masaki Yamamoto, Miki Nagao, Makoto Ohnishi, Motoyuki Sugai and 1 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Serotype distribution and antimicrobial resistance ofJournal of medical microbiology · 2025
    Article
  3. Article
  4. Article
  5. Ultrastructural, metabolic and genetic characteristics of determinants facilitating the acquisition of macrolide resistance by Streptococcus pneumoniae.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2024
    Article
  6. Bacteriological characteristics and changes ofEpidemiology and infection · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Koh ShinoharaDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-8934-0375
Takao FujisawaNational Hospital Organization Mie National Hospital, Tsu, Japan.
Bin ChangBacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Yutaka ItoNagoya City University, Graduate School of Medical Science, Nagoya, Japan.ORCID 0000-0002-1538-5551
Shigeru SugaNational Hospital Organization Mie National Hospital, Tsu, Japan.
Yasufumi MatsumuraDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-8595-8944
Masaki YamamotoDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Miki NagaoDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Makoto OhnishiBacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Motoyuki SugaiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0001-9252-7739
Satoshi NakanoDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-8987-0250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus pneumoniae is a common bacterial pathogen that causes infections in children worldwide, even after administration of the pneumococcal conjugate vaccine. S. pneumoniae serotype 35B, especially the clonal complex 558 (CC558) lineage, has emerged globally following implementation of the 13-valent pneumococcal conjugate vaccine. Serotype 35B strains are also associated with multidrug resistance to both β-lactams and non-β-lactam drugs. In addition, a novel serotype, 35D, which is closely related to 35B and differs in polysaccharide structure, was recently reported. However, the genetic relationship among globally disseminating serotype 35B and D (35B/D) strains remains unknown. To investigate the molecular epidemiology of global serotype 35B/D strains, we conducted a genomic analysis of serotype 35B/D strains from various continents, including those from the Japanese national surveillance collection. A total of 87 isolates were identified as serotype 35B/D in the Japanese surveillance collection (

Indexed as

Pneumococcal InfectionsStreptococcus pneumoniaeAnti-Bacterial AgentsChildHumansJapanPhylogenyPneumococcal VaccinesSerogroupVaccines, ConjugateAnti-Bacterial AgentsPneumococcal VaccinesVaccines, Conjugatemultidrug resistancepneumococcal diseaseserotype 35Bserotype 35DStreptococcus pneumoniaewhole-genome sequencing

Identifiers

PMID36651739
PMCPMC9933736

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.