Evidence map›Paper›PMID 36652486›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Nitro-oleic acid regulates T cell activation through post-translational modification of calcineurin.

Ángel Bago, M Laura Cayuela, Alba Gil, Enrique Calvo, Jesús Vázquez, Antonio Queiro, Francisco J Schopfer, Rafael Radi, Juan M Serrador, Miguel A Íñiguez

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Lipoxin AbioRxiv : the preprint server for biology · 2024
    Article
  10. Scd-1 deficiency promotes the differentiation of CD8Frontiers in cellular and infection microbiology · 2024
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Ángel BagoImmune System Development and Function Unit, Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid 28049, Spain.
M Laura CayuelaImmune System Development and Function Unit, Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid 28049, Spain.
Alba GilImmune System Development and Function Unit, Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid 28049, Spain.
Enrique CalvoCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid 28029, Spain.
Jesús VázquezCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid 28029, Spain.ORCID 0000-0003-1461-5092
Antonio QueiroDepartment of Medical Biochemistry and Biophysics, Division of Vascular Biology, Karolinska Institutet, Stockholm 17177, Sweden.
Francisco J SchopferDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Rafael RadiDepartamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo 11800, Uruguay.ORCID 0000-0002-1114-1875
Juan M SerradorImmune System Development and Function Unit, Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid 28049, Spain.ORCID 0000-0003-4710-3077
Miguel A ÍñiguezImmune System Development and Function Unit, Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid 28049, Spain.ORCID 0000-0001-8262-6119
Consejo Superior de Investigaciones Científicas · ESSpanish National Centre for Cardiovascular Research · ESKarolinska Institutet · SEUniversidad de la República de Uruguay · UYUniversity of Pittsburgh · US

Funding

Formation and metabolism of nitrated fatty acidsR01GM125944 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHOPFER, FRANCISCO JOSE · 2018 to 2025
$3.4M
Predominant protective role in hepatic steatosis and obesity by fish oil-derived furansR01DK112854 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHOPFER, FRANCISCO JOSE · 2018 to 2021
$1.6M
NIDDK NIH HHS R01 DK112854NIGMS NIH HHS R01 GM125944
6 · The paper itself

Abstract

Nitro-fatty acids (NO

Indexed as

CalcineurinNitrogen DioxideAnimalsFatty AcidsMiceNitro CompoundsOleic AcidOleic AcidsProtein Processing, Post-TranslationalCalcineurinCXA-10Fatty AcidsNitro CompoundsNitrogen DioxideOleic AcidOleic AcidscalcineurininflammationNFATnitro-fatty acidsT cells

Identifiers

PMID36652486
PMCPMC9942794
OpenAlexW4317360185

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.