Evidence map›Paper›PMID 36656378›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2023

The influence of renal disease on outcomes and cardiac remodeling following surgical mitral valve replacement.

Ryaan El-Andari, Sabin J Bozso, Nicholas M Fialka, Jimmy J H Kang, Dana Boe, Yongzhe Hong, Michael C Moon, Darren H Freed, Jayan Nagendran, Jeevan Nagendran

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ryaan El-AndariDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Sabin J BozsoDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Nicholas M FialkaFaculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Jimmy J H KangDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Dana BoeDepartment of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, AB, Canada.
Yongzhe HongDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Michael C MoonDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Darren H FreedDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Jayan NagendranDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Jeevan NagendranDivision of Cardiac Surgery, Department of Surgery, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, AB, Canada. jeevan@ualberta.ca.ORCID http://orcid.org/0000-0002-2050-6717
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesChronic kidney disease (CKD) is increasingly prevalent in patients undergoing mitral valve replacement (MVR). While CKD is known to result in suboptimal outcomes for patients with mitral valve disease, there is limited literature evaluating the long-term outcomes and cardiac remodeling of patients with CKD undergoing MVR. We present the first analysis coupling long-term outcomes of combined morbidity, mortality, and cardiac remodeling post-MVR in patients with CKD.

methodsPatients with varying degrees of CKD undergoing MVR from 2004 to 2018 were compared. Patients were grouped by estimated glomerular filtration rate (eGFR) > 90 mL/min/1.73m

resultsOne-year mortality was significantly increased in patients with eGFR < 30 (p = 0.023). Mortality at 7 years was significantly increased in patients with eGFR < 30 mL/min/1.73m

conclusionsCKD is predictive of inferior clinical and echocardiographic outcomes in patients undergoing MVR and consequently requires careful preoperative consideration and planning. Further investigation into optimizing the postoperative outcomes of this patient population is necessary.

Indexed as

Cardiac Surgical ProceduresRenal Insufficiency, ChronicGlomerular Filtration RateHumansMitral ValveTreatment OutcomeVentricular RemodelingMitral valve diseaseMitral valve replacementRenal disease

Identifiers

PMID36656378
OpenAlexW4317480393

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.