ArticleScience (New York, N.Y.)2023
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 39 citations in OpenAlex.
- SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities.Cancer discovery · 2026Article
- BTG1 Mutation Correlates with Inferior Prognosis in Diffuse Large B-Cell Lymphoma.Cancer research and treatment · 2026Article
- CCL19bioRxiv : the preprint server for biology · 2026Article
- Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq.Nature communications · 2026Article
- Molecular Pathogenesis and Therapeutic Response of Diffuse Large B Cell Lymphoma Genetic Subtypes.Annual review of cancer biology · 2026Article
- Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade.Nature medicine · 2026Article
- Rethinking the microenvironment's role in chemical-induced malignancy.Toxicological sciences : an official journal of the Society of Toxicology · 2026Review
- The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase.Nucleic acids research · 2026Article
- Mouse models of B cell lymphomas on the basis of genetic features.Frontiers in immunology · 2026Review
- T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.Nature cell biology · 2026Article
- Article
- In vivo CRISPR screening reveals cooperation of KMT2D and TP53 deficiencies in B-cell lymphomagenesis.Blood advances · 2025Article
- Guardians of silence: transcriptional networks in T cell quiescence.Experimental & molecular medicine · 2025Review
- Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma.Blood cancer discovery · 2025Article
- Audit of B-cell cancer genes.Blood advances · 2025Review
- PDL1-expressing macrophages infiltrate diffuse large B-cell lymphoma and promote lymphoma growth in a MYC-driven experimental model.Blood cancer journal · 2025Article
- Structure of the nucleosome-bound human BCL7A.Nucleic acids research · 2025Article
- Identification of genomic biomarkers of disease progression and survival in primary CNS lymphoma.Blood advances · 2025Article
- Understanding the intrinsic biology of diffuse large B-cell lymphoma: recent advances and future prospects.International journal of hematology · 2025Review
- Ferroptosis contributes to immunosuppression.Frontiers of medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
35 authors at 7 institutions in 6 countries.
Coraline MlynarczykDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-6750-0240
Matt TeaterDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0001-9415-1659
Juhee PaeLaboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.ORCID 0000-0003-0676-0935
Christopher R ChinDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-2140-3197
Ling WangDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Theinmozhi ArulrajDepartment of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.ORCID 0000-0002-7258-7512
Darko BarisicDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Antonin PapinDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-4801-8002
Kenneth B HoehnDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0411-4307
Ekaterina KotsDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
Jonatan ErschingLaboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
Arnab BandyopadhyayDepartment of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.ORCID 0000-0002-5149-1714
Ersilia BarinDepartment of Pharmacology and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Hui Xian PohDepartment of Pharmacology and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0003-4286-9217
Chiara M EvansMolecular Pharmacology Program and Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, and Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-1083-7886
Amy ChadburnDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Zhengming ChenDivision of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Hao ShenDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Hannah M IslesDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-6019-4842
Benedikt PelzerDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-1892-3650
Ioanna TsialtaDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Ashley S DoaneDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-1489-1786
Huimin GengDepartment of Laboratory Medicine, University of California, San Francisco, CA, USA.
Muhammad Hassan RehmanDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-0096-8076
Jonah MelnickDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Wyatt MorganDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-9725-8846
Diu T T NguyenMolecular Pharmacology Program and Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, and Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-8328-0009
Olivier ElementoDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-8061-9617
Michael G KharasMolecular Pharmacology Program and Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, and Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-1165-6991
Samie R JaffreyDepartment of Pharmacology and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
David W ScottCentre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada.ORCID 0000-0002-0435-5947
George KhelashviliInstitute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
Michael Meyer-HermannDepartment of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.ORCID 0000-0002-4300-2474
Gabriel D VictoraLaboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-8807-348X
Ari MelnickDivision of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-8074-2287
Cornell University · USHelmholtz Centre for Infection Research · DEMemorial Sloan Kettering Cancer Center · USRockefeller University · USSpinal Cord Injury BC · CAUniversity of California, San Francisco · USYale University · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4MClinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0MDisparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2MCANCER PHARMACOLOGYT32CA062948 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LORRAINE J GUDAS · 1994 to 2026
$12.1MMechanisms of epitranscriptomic regulation in cancerR01CA186702 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY, Michael Kharas · 2014 to 2026
$8.0MTargeting Epigenetic Circuits in B-Cell LymphomasR35CA220499 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MELNICK, ARI M. · 2018 to 2024
$7.2MUncovering the role for MSI2 network in hematopoietic stem cellsR01DK101989 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI Michael Kharas, Vijay Ganesh Sankaran · 2014 to 2026
$6.2MMolecular control of germinal center selection and affinity maturationR01AI139117 · NIAID · ROCKEFELLER UNIVERSITY · PI Gabriel D Victora · 2018 to 2026
$3.9MCOMPUTATIONAL TOOLS FOR THE ANALYSIS OF HIGH-THROUGHPUT IMMUNOGLOBULIN SEQUENCING EXPERIMENTSR01AI104739 · NIAID · YALE UNIVERSITY · PI KLEINSTEIN, STEVEN H. · 2014 to 2022
$3.6MThe identification and validation of mechanisms and biomarkers for relapse in diffuse large B-cell lymphoma (Administrative Supplement)R01CA194547 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ELEMENTO, OLIVIER, TAM, WAYNE · 2015 to 2019
$2.6MRole of Chromatin Remodeling Complex BAF in Immunity and LymphomaK99CA246080 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI BARISIC, DARKO · 2020 to 2022
$381kRole of histone demethylated LSD1 as an epigenetic dependency in lymphomaK99CA212276 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHATZI, KATERINA · 2016 to 2017
$298kNCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCI NIH HHS F31 CA220981NCI NIH HHS F31 CA254302NCI NIH HHS F31 CA257204NCI NIH HHS K99 CA212276NCI NIH HHS K99 CA246080NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA186702NCI NIH HHS R01 CA194547NCI NIH HHS R35 CA220499NCI NIH HHS T32 CA062948NIAID NIH HHS R01 AI104739NIAID NIH HHS R01 AI139117NIDDK NIH HHS R01 DK101989
Abstract
Multicellular life requires altruistic cooperation between cells. The adaptive immune system is a notable exception, wherein germinal center B cells compete vigorously for limiting positive selection signals. Studying primary human lymphomas and developing new mouse models, we found that mutations affecting
Indexed as
B-LymphocytesCell Transformation, NeoplasticLymphoma, Large B-Cell, DiffuseNeoplasm ProteinsAnimalsAntibody AffinityGerminal CenterHumansMiceMutationSelection, GeneticBTG1 protein, humanBtg1 protein, mouseNeoplasm Proteins
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.