Evidence map›Paper›PMID 36669014›Full record

ArticleVeterinary sciences2022

Derivation of the Omega-3 Index from EPA and DHA Analysis of Dried Blood Spots from Dogs and Cats.

William S Harris, Kristina H Jackson, Heather Carlson, Nils Hoem, Tonje E Dominguez, Lena Burri

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

William S HarrisFatty Acid Research Institute, Sioux Falls, SD 57106, USA.ORCID 0000-0003-3042-9353
Kristina H JacksonDepartment of Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD 57105, USA.ORCID 0000-0003-3445-8370
Heather CarlsonAll-City Pet Care Veterinary Emergency Hospital, Sioux Falls, SD 57105, USA.
Nils HoemAker BioMarine Antarctic AS, NO-1327 Lysaker, Norway.
Tonje E DominguezAker BioMarine Antarctic AS, NO-1327 Lysaker, Norway.
Lena BurriAker BioMarine Antarctic AS, NO-1327 Lysaker, Norway.ORCID 0000-0002-0099-504X
BioMar (Norway) · NOUniversity of South Dakota · US

Funding

Aker Biomarine Antarctic AS 00001
6 · The paper itself

Abstract

The Omega-3 Index (O3I) is the red blood cell (RBC) eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) content expressed as a percentage of total RBC fatty acids. Although a validated biomarker of omega-3 status in humans, little is known about the O3I status of dogs and cats; species in which omega-3 fatty acids have known health benefits. The purpose of this study was to develop equations to predict the O3I in these species from a dried blood spot (DBS) analysis. Random blood samples from 33 dogs and 10 cats were obtained from a community veterinary clinic. DBS and RBC samples were analyzed for fatty acid composition. For both species, the R2 between the DBS EPA + DHA value and the O3I was >0.96 (p < 0.001). The O3I was roughly 75% lower in dogs and cats than in humans. We conclude that the O3I can be estimated from a DBS sample, and the convenience of DBS collection should facilitate omega-3 research in these companion animals.

Indexed as

biomarkerscatsdocosahexaenoic aciddogseicosapentaenoic aciderythrocytesfish oilomega-3 fatty acidsomega-3 index

Identifiers

PMID36669014
PMCPMC9863621
OpenAlexW4313260331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.