Evidence map›Paper›PMID 36671588›Full record

ArticleBioengineering (Basel, Switzerland)2022

Mice Placental ECM Components May Provide A Three-Dimensional Placental Microenvironment.

Rodrigo da Silva Nunes Barreto, Ana Claudia Oliveira Carreira, Mônica Duarte da Silva, Leticia Alves Fernandes, Rafaela Rodrigues Ribeiro, Gustavo Henrique Doná Rodrigues Almeida, Bruna Tassia Dos Santos Pantoja, Milton Yutaka Nishiyama Junior, Maria Angelica Miglino

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rodrigo da Silva Nunes BarretoDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.ORCID 0000-0001-5240-6959
Ana Claudia Oliveira CarreiraDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.
Mônica Duarte da SilvaDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.ORCID 0000-0002-9736-8113
Leticia Alves FernandesDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.ORCID 0000-0003-0129-7523
Rafaela Rodrigues RibeiroDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.
Gustavo Henrique Doná Rodrigues AlmeidaDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.ORCID 0000-0003-2640-8250
Bruna Tassia Dos Santos PantojaDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.ORCID 0000-0002-9164-1940
Milton Yutaka Nishiyama JuniorLaboratory for Applied Toxinology, CeTIS, Butantan Institute, São Paulo CEP 05503-900, Brazil.ORCID 0000-0002-2410-0562
Maria Angelica MiglinoDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo Cidade Universitária, Butantã CEP 05508-270, Brazil.

Funding

Coordination for the Improvement of Higher Education Personnel PNPD 88887.474193/2020-00Coordination for the Improvement of Higher Education Personnel PROEX 88882.327806/2014-01São Paulo Research Foundation 2014/50844-3Universidade de São Paulo 2015/14535-9
6 · The paper itself

Abstract

Bioethical limitations impair deeper studies in human placental physiology, then most studies use human term placentas or murine models. To overcome these challenges, new models have been proposed to mimetize the placental three-dimensional microenvironment. The placental extracellular matrix plays an essential role in several processes, being a part of the establishment of materno-fetal interaction. Regarding these aspects, this study aimed to investigate term mice placental ECM components, highlighting its collagenous and non-collagenous content, and proposing a potential three-dimensional model to mimetize the placental microenvironment. For that, 18.5-day-old mice placenta, both control and decellularized (

Indexed as

animal modelsmaterno-fetal interfaceplacental ECM proteomics

Identifiers

PMID36671588
PMCPMC9855196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.