Evidence map›Paper›PMID 36672619›Full record

ArticleBiomedicines2023

Intrarenal Dopaminergic System Is Dysregulated in SS-

Usman M Ashraf, Ealla Atari, Fawaz Alasmari, Harshal Waghulde, Vikash Kumar, Youssef Sari, Sonia M Najjar, Pedro A Jose, Sivarajan Kumarasamy

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Usman M AshrafDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
Ealla AtariDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
Fawaz AlasmariDepartment of Pharmacology and Experimental Therapeutics, University of Toledo College of Pharmacy & Pharmaceutical Sciences, Toledo, OH 43614, USA.ORCID 0000-0003-2382-5892
Harshal WaghuldeDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
Vikash KumarDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Youssef SariDepartment of Pharmacology and Experimental Therapeutics, University of Toledo College of Pharmacy & Pharmaceutical Sciences, Toledo, OH 43614, USA.ORCID 0000-0002-6761-9786
Sonia M NajjarDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.ORCID 0000-0001-6209-8902
Pedro A JoseDepartment of Medicine, Division of Kidney Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC 20052, USA.
Sivarajan KumarasamyDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0000-0003-1327-2294
University of Toledo · USOhio University · USGeorge Washington University · USMedical College of Wisconsin · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOSE, PEDRO A. · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
SUBSTRATES AND INSULIN RECEPTOR ENDOCYTOSISR01DK054254 · NIDDK · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI NAJJAR, SONIA M. · 2000 to 2021
$5.8M
Lipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6M
CEACAM1: A link between metabolic and cardiovascular diseasesR01HL112248 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI NAJJAR, SONIA M. · 2012 to 2016
$1.9M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL112248NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK054254NIDDK NIH HHS R01 DK119652NIH HHS R01 DK039308NIH HHS R01 DK054254NIH HHS R01 DK119652NIH HHS R01 HL074940NIH HHS R01 HL112248
6 · The paper itself

Abstract

The genetic and molecular basis of developing high blood pressure and renal disease are not well known.

Indexed as

blood pressureDahl salt-sensitive ratsdopaminekidneyResp18

Identifiers

PMID36672619
PMCPMC9855394
OpenAlexW4313389285

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.