Evidence map›Paper›PMID 36673024›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Genomic Characterization of Rare Primary Cardiac Sarcoma Entities.

Livia Gozzellino, Margherita Nannini, Carmine Pizzi, Ornella Leone, Barbara Corti, Valentina Indio, Chiara Baldovini, Pasquale Paolisso, Alberto Foà, Davide Pacini and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Livia GozzellinoDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.
Margherita NanniniDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2103-1960
Carmine PizziDepartment of Experimental Diagnostic and Specialty Medicine, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.
Ornella LeoneDivision of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.
Barbara CortiDivision of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.
Valentina IndioDepartment of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-8854-3821
Chiara BaldoviniDivision of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.ORCID 0000-0002-1499-4654
Pasquale PaolissoDepartment of Experimental Diagnostic and Specialty Medicine, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.
Alberto FoàDepartment of Experimental Diagnostic and Specialty Medicine, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.
Davide PaciniCardiac Surgery Unit, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.ORCID 0000-0002-4298-3792
Gianluca FolesaniCardiac Surgery Unit, IRCCS Azienda Ospedaliero-Universitaria, 40138 Bologna, Italy.
Angela SchipaniDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CS Utrecht, The Netherlands.
Alice CostaDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-0809-2512
Gianandrea PasquinelliDivision of Pathology, IRCCS Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0003-1506-1829
Maria Abbondanza PantaleoDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.
Annalisa AstolfiDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2732-0747
Azienda USL di Bologna · ITUniversity of Bologna · ITUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cardiac sarcomas are considered rare malignant entities associated with poor prognosis. In fact, knowledge regarding their gene signature and possible treatments is still limited. In our study, whole-transcriptome sequencing on formalin-fixed paraffin-embedded (FFPE) samples from one cardiac osteosarcoma and one cardiac leiomyosarcoma was performed, to investigate their mutational profiles and to highlight differences and/or similarities to other cardiac histotypes. Both cases have been deeply detailed from a pathological point of view. The osteosarcoma sample presented mutations involving

Indexed as

bioinformaticscardiac sarcomasleiomyosarcomaosteosarcomawhole-transcriptome sequencing

Identifiers

PMID36673024
PMCPMC9858520
OpenAlexW4313646599

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.