Evidence map›Paper›PMID 36673135›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Deep Learning in Optical Coherence Tomography Angiography: Current Progress, Challenges, and Future Directions.

Dawei Yang, An Ran Ran, Truong X Nguyen, Timothy P H Lin, Hao Chen, Timothy Y Y Lai, Clement C Tham, Carol Y Cheung

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Quantitative Characterization of Retinal Features in Translated OCTA.medRxiv : the preprint server for health sciences · 2024
    Article
  11. Article
  12. Article
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  15. Quantitative characterization of retinal features in translated OCTA.Experimental biology and medicine (Maywood, N.J.) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Dawei YangDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-4826-9060
An Ran RanDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-4592-4867
Truong X NguyenDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-8505-6593
Timothy P H LinDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hao ChenDepartment of Computer Science and Engineering, The Hong Kong University of Science and Technology, Hong Kong SAR, China.
Timothy Y Y LaiDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-7832-6428
Clement C ThamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-4407-6907
Carol Y CheungDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-9672-1819
Chinese University of Hong Kong · HKHong Kong University of Science and Technology · HK

Funding

CUHK Direct Grant 4054419CUHK Direct Grant 4054487
6 · The paper itself

Abstract

Optical coherence tomography angiography (OCT-A) provides depth-resolved visualization of the retinal microvasculature without intravenous dye injection. It facilitates investigations of various retinal vascular diseases and glaucoma by assessment of qualitative and quantitative microvascular changes in the different retinal layers and radial peripapillary layer non-invasively, individually, and efficiently. Deep learning (DL), a subset of artificial intelligence (AI) based on deep neural networks, has been applied in OCT-A image analysis in recent years and achieved good performance for different tasks, such as image quality control, segmentation, and classification. DL technologies have further facilitated the potential implementation of OCT-A in eye clinics in an automated and efficient manner and enhanced its clinical values for detecting and evaluating various vascular retinopathies. Nevertheless, the deployment of this combination in real-world clinics is still in the "proof-of-concept" stage due to several limitations, such as small training sample size, lack of standardized data preprocessing, insufficient testing in external datasets, and absence of standardized results interpretation. In this review, we introduce the existing applications of DL in OCT-A, summarize the potential challenges of the clinical deployment, and discuss future research directions.

Indexed as

artificial intelligencedeep learningdiabetic macular ischemiadiabetic retinopathyglaucomaimage qualitymedical image analysisoptical coherence tomography angiographyretinal vascular diseases

Identifiers

PMID36673135
PMCPMC9857993
OpenAlexW4316469714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.