ReviewInternational journal of environmental research and public health2023
Chronic Kidney Disease and Periodontitis Interplay-A Narrative Review.
Review in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluating Dickkopf-1 as a biomarker: insights into periodontitis, rheumatoid arthritis, and their comorbidity-a systematic review and meta-analysis.Frontiers in dental medicine · 2025Pooled it
- The Impact of Chronic Kidney Disease on Oral Health: A Narrative Review.Journal of clinical medicine · 2026Review
- Short-term assessment of non-surgical periodontal therapy reduces oral pathogens and pro-inflammatory cytokines, enhancing clinical outcomes in patients with chronic kidney disease.BMC oral health · 2026Article
- Association of periodontitis with reduced kidney function and albuminuria in early chronic kidney disease: a population-based study.International journal of oral science · 2026Article
- The Oral Microbiome and Systemic Health: Current Insights into the Mouth-Body Connection.Life (Basel, Switzerland) · 2026Review
- Oral health and chronic kidney disease in Brazil: a population-based analysis of the 2019 National Health Survey.BMC public health · 2026Article
- Prevalence of ear disease in small-breed dogs undergoing cone-beam computed tomography for dental procedures.Frontiers in veterinary science · 2026Article
- Oral microbiota and urinary system diseases: from mechanistic insights to clinical implications-a comprehensive review.Frontiers in dental medicine · 2026Review
- Periodontitis as a potential amplifier of diabetes-related genitourinary complications: evidence gradients and mechanistic insights into the inflammation-microvascular injury axis.Frontiers in cellular and infection microbiology · 2026Review
- Oral health in professional Slovak soccer players: Assessment of dental risks, subgingival microbiota and genetic influences.PloS one · 2026Article
- Oral Health Assessment in Adolescents with End-Stage Chronic Kidney Disease.Journal of clinical medicine · 2025Article
- Association between chronic kidney disease and tooth loss among Korean adults: results from the Korea National Health And Nutrition Examination Survey (KNHANES), 2013-2018.Renal failure · 2025Article
- Oxidative Stress Markers Associated with Gingival Inflammatory Status in Children with Leukemia.Diagnostics (Basel, Switzerland) · 2025Article
- The relationship between periodontitis and proteinuria in chronic kidney disease: A review.Medicina oral, patologia oral y cirugia bucal · 2025Review
- Periodontitis, accelerated biological aging, and advanced stages in cardiovascular-kidney-metabolic syndrome in U.S. Adults: A mediation analysis.Diabetes research and clinical practice · 2025Article
- Article
- Evaluating the Association Between Neutrophil Gelatinase-Associated Lipocalin Levels and Periodontal Health Status in Patients With Chronic Kidney Disease.Mediators of inflammation · 2025Article
- Exploring the association of calbindin -D28K in renal dialysis with oral health: a comprehensive review.Frontiers in oral health · 2025Review
- Inflammation and Arterial Stiffness as Drivers of Cardiovascular Risk in Kidney Disease.Cardiorenal medicine · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis (PO), a chronic microbially-induced inflammation of the supporting tissues of the tooth, is linked to various systemic diseases. We analyze its bidirectional relationship to chronic kidney disease (CKD), a major health-care problem with impressive excess mortality. Overwhelming associative relationship between CKD and PO are analyzed. Major pathophysiologic mechanisms that link CKD to PO are then presented: systemic inflammation, endothelial dysfunction, and imbalance of oxidative stress characteristic of CKD have a role in PO development and might influence escape mechanisms of oral microbiota. Subclinical local and systemic inflammation induced by PO might influence in turn CKD outcomes. Homeostatic changes induced by CKD such as mineral bone disorders, acidosis, uremic milieu, or poor salivary flow are also relevant for the occurrence of PO. There is insufficient evidence to recommend a standardized diagnostic and therapeutic approach regarding association of PO to CKD.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.