Evidence map›Paper›PMID 36674723›Full record

ArticleInternational journal of molecular sciences2023

Transcriptomic Analysis of Glycosylation and Neuroregulatory Pathways in Rodent Models in Response to Psychedelic Molecules.

Anup M Oommen, Katherine J Roberts, Lokesh Joshi, Stephen Cunningham

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Anup M OommenAdvanced Glycoscience Research Cluster (AGRC), University of Galway, H91 W2TY Galway, Ireland.
Katherine J RobertsDepartment of Health and Behaviour Studies, Teachers College, Columbia University, New York, NY 10027, USA.ORCID 0000-0001-6528-089X
Lokesh JoshiAdvanced Glycoscience Research Cluster (AGRC), University of Galway, H91 W2TY Galway, Ireland.
Stephen CunninghamAdvanced Glycoscience Research Cluster (AGRC), University of Galway, H91 W2TY Galway, Ireland.ORCID 0000-0003-0373-6948
Ollscoil na Gaillimhe – University of Galway · IEColumbia University · US

Funding

European Union Horizon 2020 research and innovation programme, grant agreement No 825033Science Foundation Ireland 13/RC/2073_P2Science Foundation Ireland 21/FIP/DO/9966
6 · The paper itself

Abstract

The potential for psychedelic molecules in impacting cognitive flexibility has long been supported and acknowledged across scientific reports. In the current study, an approach leveraging knowledge-based gene-set information analysis has been adopted to explore the potential impact of psychedelic molecules on both glycosylation, (a post-translational modifications (PTM)) and on neuro-regulatory pathways. Though limitations and restrictions rise from the scarcity of publicly available 'omics' data, targeted analysis enabled us to identify a number of key glycogenes (

Indexed as

HallucinogensGene Expression ProfilingGlycosylationTranscriptomeHallucinogensenrichment analysisglycoconjugatesglycosylationmolecular pathwaysneuro-regulatorypsychedelic

Identifiers

PMID36674723
PMCPMC9867456
OpenAlexW4313895193

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.