Evidence map›Paper›PMID 36675097›Full record

ReviewInternational journal of molecular sciences2023

Gender Differences and Cardiometabolic Risk: The Importance of the Risk Factors.

Antonella Meloni, Christian Cadeddu, Lucia Cugusi, Maria Pia Donataccio, Martino Deidda, Susanna Sciomer, Sabina Gallina, Cristina Vassalle, Federica Moscucci, Giuseppe Mercuro and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Arquivos brasileiros de cardiologia · 2024
    Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Physical Activity and Its Impact on Cardiometabolic Disorders.Handbook of experimental pharmacology · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The impact of sex on blood pressure.Current opinion in nephrology and hypertension · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Antonella MeloniDepartment of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-2284-8585
Christian CadedduDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-2823-1797
Lucia CugusiDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7650-0640
Maria Pia DonataccioCardiology Unit, European Hospital, 00149 Rome, Italy.
Martino DeiddaDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-3725-7614
Susanna SciomerDepartment of Clinical and Internal Medicine, Anesthesiology and Cardiovascular Sciences, University of Rome "Sapienza", Policlinico Umberto I, 00185 Roma, Italy.ORCID 0000-0001-9487-833X
Sabina GallinaDepartment of Neuroscience, Imaging and Clinical Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-0263-4851
Cristina VassalleMedicina di Laboratorio, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0003-3438-6450
Federica MoscucciDepartment of Clinical and Internal Medicine, Anesthesiology and Cardiovascular Sciences, University of Rome "Sapienza", Policlinico Umberto I, 00185 Roma, Italy.ORCID 0000-0002-9385-9097
Giuseppe MercuroDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.
Silvia MaffeiEndocrinologia Cardiovascolare Ginecologica ed Osteoporosi, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-5081-1253
Fondazione Toscana Gabriele Monasterio · ITUniversity of Cagliari · ITPoliclinico Umberto I · ITEuropean Hospital · ITUniversity of Chieti-Pescara · ITUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome (Mets) is a clinical condition characterized by a cluster of major risk factors for cardiovascular disease (CVD) and type 2 diabetes: proatherogenic dyslipidemia, elevated blood pressure, dysglycemia, and abdominal obesity. Each risk factor has an independent effect, but, when aggregated, they become synergistic, doubling the risk of developing cardiovascular diseases and causing a 1.5-fold increase in all-cause mortality. We will highlight gender differences in the epidemiology, etiology, pathophysiology, and clinical expression of the aforementioned Mets components. Moreover, we will discuss gender differences in new biochemical markers of metabolic syndrome and cardiovascular risk.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Metabolic SyndromeHumansRisk FactorsSex Factorscardiovascular diseasegendermetabolic syndromerisk factors

Identifiers

PMID36675097
PMCPMC9864423
OpenAlexW4316039026

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.