Evidence map›Paper›PMID 36675165›Full record

ArticleInternational journal of molecular sciences2023

siRNA-Mediated

Ivan V Chernikov, Yaroslav Yu Staroseletz, Irina S Tatarnikova, Aleksandra V Sen'kova, Innokenty A Savin, Andrey V Markov, Evgeniya B Logashenko, Elena L Chernolovskaya, Marina A Zenkova, Valentin V Vlassov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Frontiers in immunology · 2025
    Review
  7. PDGFRα-positive cell-derived TIMP-1 modulates adaptive immune responses to influenza A viral infection.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  8. Article
  9. Article
  10. Advances in Biomarkers for Diagnosis and Treatment of ARDS.Diagnostics (Basel, Switzerland) · 2023
    Review
  11. TIMP-1 and its potential diagnostic and prognostic value in pulmonary diseases.Chinese medical journal pulmonary and critical care medicine · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ivan V ChernikovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Yaroslav Yu StaroseletzInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Irina S TatarnikovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0003-2558-8114
Aleksandra V Sen'kovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0001-5729-9910
Innokenty A SavinInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0002-3032-858X
Andrey V MarkovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0001-7569-9555
Evgeniya B LogashenkoInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0001-8977-5395
Elena L ChernolovskayaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0001-9689-005X
Marina A ZenkovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0003-4044-1049
Valentin V VlassovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Institute of Chemical Biology and Fundamental Medicine · RU

Funding

Russian Science Foundation 19-74-30011
6 · The paper itself

Abstract

Acute lung injury is a complex cascade process that develops in response to various damaging factors, which can lead to acute respiratory distress syndrome. Within this study, based on bioinformatics reanalysis of available full-transcriptome data of acute lung injury induced in mice and humans by various factors, we selected a set of genes that could serve as good targets for suppressing inflammation in the lung tissue, evaluated their expression in the cells of different origins during LPS-induced inflammation, and chose the tissue inhibitor of metalloproteinase

Indexed as

Acute Lung InjuryRNA, Small InterferingAnimalsHumansInflammationLipopolysaccharidesLungMiceMice, Inbred C57BLPhenotypeTissue Inhibitor of Metalloproteinase-1LipopolysaccharidesRNA, Small InterferingTIMP1 protein, humanTimp1 protein, mouseTissue Inhibitor of Metalloproteinase-1acute lung injurybioinformatics analysischemically modified siRNAIL6inflammationLPSTIMP1

Identifiers

PMID36675165
PMCPMC9865963
OpenAlexW4316372004

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.