Evidence map›Paper›PMID 36676706›Full record

ReviewMedicina (Kaunas, Lithuania)2022

The Role of NLRP3 Inflammasome in IgA Nephropathy.

Xiaofang Wu, Lei Zhao, Kailong Li, Jurong Yang

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Inflammation in glomerular diseases.Frontiers in immunology · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaofang WuDepartment of Nephrology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 400120, China.ORCID 0000-0002-5102-0314
Lei ZhaoDepartment of Nephrology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 400120, China.
Kailong LiDepartment of Nephrology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 400120, China.
Jurong YangDepartment of Nephrology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 400120, China.ORCID 0000-0002-6792-4617
Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerular disease worldwide today. The NLRP3 inflammasome is a polyprotein complex and an important participant in inflammation. Accumulating studies have shown that the NLRP3 inflammasome participates in a variety of kidney diseases, including IgAN. This review focuses on the role of the NLRP3 inflammasome in IgAN and summarizes multiple involved pathways, which may provide novel treatments for IgAN treatment.

Indexed as

Glomerulonephritis, IGAHumansInflammasomesInflammationNLR Family, Pyrin Domain-Containing 3 ProteinInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinautophagyexosomesIgA nephropathyNF-κBNLRP3 inflammasomeROS

Identifiers

PMID36676706
PMCPMC9866943
OpenAlexW4313361216

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.