Evidence map›Paper›PMID 36677572›Full record

ArticleMolecules (Basel, Switzerland)2023

Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 M

Andrea Citarella, Davide Moi, Martina Pedrini, Helena Pérez-Peña, Stefano Pieraccini, Claudio Stagno, Nicola Micale, Tanja Schirmeister, Giulia Sibille, Giorgio Gribaudo and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrea CitarellaDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0001-5881-7142
Davide MoiDipartimento di Scienze Chimiche e Geologiche, University of Cagliari, Cittadella Universitaria-S.S. 554 bivio per Sestu, 09042 Monserrato, Italy.ORCID 0000-0002-2470-9351
Martina PedriniDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0003-4332-7241
Helena Pérez-PeñaDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0001-7938-4307
Stefano PieracciniDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0002-7672-0720
Claudio StagnoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
Nicola MicaleDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-9294-6033
Tanja SchirmeisterDepartment of Medicinal Chemistry, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany.
Giulia SibilleDepartment of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, Italy.ORCID 0000-0002-2869-357X
Giorgio GribaudoDepartment of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, Italy.ORCID 0000-0002-1583-9146
Alessandra SilvaniDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0002-0397-2636
Daniele PassarellaDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0001-6180-9581
Clelia GianniniDepartment of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0003-3376-8350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 M

Indexed as

Antiviral AgentsDiazomethaneProtease InhibitorsSARS-CoV-2Molecular Docking SimulationAntiviral AgentsDiazomethaneProtease InhibitorscoronavirusCOVID-19cysteine proteasesdiazirinesenzymatic inhibitorsSARS-CoV-2SARS-CoV-2 Mpro

Identifiers

PMID36677572
PMCPMC9864213

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.