Evidence map›Paper›PMID 36678151›Full record

ArticleNutrients2023

Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance.

Lucia Mráziková, Silvie Hojná, Petra Vaculová, Štěpán Strnad, Vladimír Vrkoslav, Helena Pelantová, Marek Kuzma, Blanka Železná, Jaroslav Kuneš, Lenka Maletínská

Open access · goldFull text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lucia MrázikováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.
Silvie HojnáInstitute of Physiology, Czech Academy of Sciences, 142 20 Prague, Czech Republic.
Petra VaculováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.
Štěpán StrnadInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.ORCID 0000-0002-0769-2420
Vladimír VrkoslavInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.ORCID 0000-0002-5126-8360
Helena PelantováInstitute of Microbiology, Czech Academy of Sciences, 142 20 Prague, Czech Republic.ORCID 0000-0002-2523-7413
Marek KuzmaInstitute of Microbiology, Czech Academy of Sciences, 142 20 Prague, Czech Republic.
Blanka ŽeleznáInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.
Jaroslav KunešInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.
Lenka MaletínskáInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZCzech Academy of Sciences · CZ

Funding

Czech Science Foundation 20-00546SEuropean Union - Next Generation EU LX22NP05104
6 · The paper itself

Abstract

Prolactin-releasing peptide (PrRP) is an anorexigenic neuropeptide that has potential for the treatment of obesity and its complications. Recently, we designed a palmitoylated PrRP31 analog (palm

Indexed as

Glucose IntoleranceInsulin ResistancePrediabetic StateAnimalsDiet, High-FatHypoglycemic AgentsLipidsLiraglutideMiceObesityProlactin-Releasing HormoneRatsRats, Inbred WKYHypoglycemic AgentsLipidsLiraglutideProlactin-Releasing Hormoneastrocytosisdiet-induced obesityglucose intolerancelipid metabolismlipidomicsliraglutidemetabolomicsprolactin-releasing peptideWistar Kyoto rats

Identifiers

PMID36678151
PMCPMC9864151
OpenAlexW4313648612

What Socratic holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.