Evidence map›Paper›PMID 36678511›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Dehydroeburicoic Acid, a Dual Inhibitor against Oxidative Stress in Alcoholic Liver Disease.

Shasha Cheng, Yi Kuang, Guodong Li, Jia Wu, Chung-Nga Ko, Wanhe Wang, Dik-Lung Ma, Min Ye, Chung-Hang Leung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Hepatoprotective Effect ofFood science & nutrition · 2026
    Article
  2. Review
  3. Comparative Efficacy ofAntioxidants (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Shasha ChengState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Yi KuangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Guodong LiState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Jia WuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Chung-Nga KoDepartment of Chemistry, Hong Kong Baptist University, Hong Kong SAR 999077, China.
Wanhe WangDepartment of Chemistry, Hong Kong Baptist University, Hong Kong SAR 999077, China.
Dik-Lung MaDepartment of Chemistry, Hong Kong Baptist University, Hong Kong SAR 999077, China.ORCID 0000-0002-9515-340X
Min YeState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Chung-Hang LeungState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.ORCID 0000-0003-2988-3786
University of Macau · MOHong Kong Baptist University · HKPeking University · CN

Funding

HKBU SKLEBA Research Grant SKLP_2223_P03National Natural Science Foundation of China 22077109, 21775131 and 82073715Science and Technology Development Fund, Macau SAR 0007/2020/A1University of Macau MYRG2019-00002-ICMS, MYRG2020-00091-ICMS and MYRG2020-00017-ICMSUniversity of Macau SKL-QRCM(UM)-2020-2022
6 · The paper itself

Abstract

Alcoholic liver disease (ALD) is a complicated disease which can lead to hepatocellular carcinoma; however, there is a lack of satisfactory therapeutics. Dehydroeburicoic acid (DEA) (

Indexed as

alcoholic liver disease (ALD)glycogen synthase kinase 3β (GSK3β)hepatoprotectiveKeap1–Nrf2 protein–protein interaction (PPI)

Identifiers

PMID36678511
PMCPMC9866905
OpenAlexW4312174147

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.