Evidence map›Paper›PMID 36678852›Full record

ReviewPharmaceutics2023

Recent Advancements in Metallic Drug-Eluting Implants.

Sadeq Alshimaysawee, Rasha Fadhel Obaid, Moaed E Al-Gazally, Andrés Alexis Ramírez-Coronel, Masoud Soroush Bathaei

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. TiOHeliyon · 2024
    Article
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  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Sadeq AlshimaysaweeFaculty of Pharmacy, Islamic University, Najaf, Iraq.
Rasha Fadhel ObaidDepartment of Biomedical Engineering, Al-Mustaqbal University College, Babylon, Iraq.
Moaed E Al-GazallyCollege of Medicine, University of Al-Ameed, Karbala, Iraq.
Andrés Alexis Ramírez-CoronelLaboratory of Psychometrics, Comparative Psychology and Ethology (LABPPCE), Universidad Católica de Cuenca, Ecuador and Universidad CES, Medellín, Colombia, Cuenca, Ecuador.
Masoud Soroush BathaeiDepartment of Materials Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.ORCID 0000-0003-1807-5150
Iraqi University · IQIslamic Azad University, Science and Research Branch · IRUniversidad Católica de Cuenca · ECUniversity of Babylon · IQUniversity of Kerbala · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade, metallic drug-eluting implants have gained significance in orthopedic and dental applications for controlled drug release, specifically for preventing infection associated with implants. Recent studies showed that metallic implants loaded with drugs were substituted for conventional bare metal implants to achieve sustained and controlled drug release, resulting in a desired local therapeutic concentration. A number of secondary features can be provided by the incorporated active molecules, including the promotion of osteoconduction and angiogenesis, the inhibition of bacterial invasion, and the modulation of host body reaction. This paper reviews recent trends in the development of the metallic drug-eluting implants with various drug delivery systems in the past three years. There are various types of drug-eluting implants that have been developed to meet this purpose, depending on the drug or agents that have been loaded on them. These include anti-inflammatory drugs, antibiotics agents, growth factors, and anti-resorptive drugs.

Indexed as

bioactive coatingsbiomaterialsbone tissue engineeringimplantsinfectionlocalized drug delivery

Identifiers

PMID36678852
PMCPMC9862589
OpenAlexW4313889587

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.