Evidence map›Paper›PMID 36678908›Full record

ReviewPharmaceutics2023

Isolation, Detection and Analysis of Circulating Tumour Cells: A Nanotechnological Bioscope.

Upama Das, Soumyabrata Banik, Sharmila Sajankila Nadumane, Shweta Chakrabarti, Dharshini Gopal, Shama Prasada Kabekkodu, Pornsak Srisungsitthisunti, Nirmal Mazumder, Rajib Biswas

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Upama DasApplied Optics and Photonics Laboratory, Department of Physics, Tezpur University, Tezpur 784028, Assam, India.
Soumyabrata BanikDepartment of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID 0000-0002-2254-1428
Sharmila Sajankila NadumaneDepartment of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Shweta ChakrabartiDepartment of Bioinformatics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Dharshini GopalDepartment of Bioinformatics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Shama Prasada KabekkoduDepartment of Cell and Molecular Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID 0000-0002-4158-3893
Pornsak SrisungsitthisuntiDepartment of Production and Robotics Engineering, Faculty of Engineering, King Mongkut's University of Technology North Bangkok, Bangkok 10800, Thailand.ORCID 0000-0002-4945-0809
Nirmal MazumderDepartment of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID 0000-0001-8068-6484
Rajib BiswasApplied Optics and Photonics Laboratory, Department of Physics, Tezpur University, Tezpur 784028, Assam, India.ORCID 0000-0001-6246-2196
Manipal Academy of Higher Education · INTezpur University · INKing Mongkut's University of Technology North Bangkok · TH

Funding

Department of Science and Technology SERB/MTR/2020/000058Indian Council of Medical Research ITR/Ad-hoc/43/2020-21, ID No. 2020-3286
6 · The paper itself

Abstract

Cancer is one of the dreaded diseases to which a sizeable proportion of the population succumbs every year. Despite the tremendous growth of the health sector, spanning diagnostics to treatment, early diagnosis is still in its infancy. In this regard, circulating tumour cells (CTCs) have of late grabbed the attention of researchers in the detection of metastasis and there has been a huge surge in the surrounding research activities. Acting as a biomarker, CTCs prove beneficial in a variety of aspects. Nanomaterial-based strategies have been devised to have a tremendous impact on the early and rapid examination of tumor cells. This review provides a panoramic overview of the different nanotechnological methodologies employed along with the pharmaceutical purview of cancer. Initiating from fundamentals, the recent nanotechnological developments toward the detection, isolation, and analysis of CTCs are comprehensively delineated. The review also includes state-of-the-art implementations of nanotechnological advances in the enumeration of CTCs, along with future challenges and recommendations thereof.

Indexed as

cancercirculating tumour cellsdetectionisolationmetastasisnanomaterialsnanotechnology

Identifiers

PMID36678908
PMCPMC9864919
OpenAlexW4316464345

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.