ReviewPolymers2023
Poly (Ether-Ether-Ketone) for Biomedical Applications: From Enhancing Bioactivity to Reinforced-Bioactive Composites-An Overview.
Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- PEEK in modern maxillofacial surgery: clinical applications, limitations and future opportunities.British dental journal · 2026Review
- Application-matched point-of-care 3D printing of functionalized polyetheretherketone (PEEK) composites for patient-specific craniomaxillofacial implants.3D printing in medicine · 2026Article
- Advances in biomaterials for sports injury prevention and rehabilitation: current status and future perspectives.Nanoscale advances · 2026Review
- Surface modifications of titanium dental implants: optimizing antibacterial activity and osteoimmunomodulation.Frontiers in bioengineering and biotechnology · 2026Review
- Integration of finite element method and artificial intelligence for evaluating PEEK composites in rib cage reconstruction process under impact conditions.Journal of materials science. Materials in medicine · 2025Article
- Review
- Computational analysis of L4-L5 interspinous process devices and interbody fusion spacers using ceramic and polymeric materials via finite element modeling and artificial intelligence.Scientific reports · 2025Article
- The Use of Non-Degradable Polymer (Polyetheretherketone) in Personalized Orthopedics-Review Article.Polymers · 2025Review
- Thermal, hardness, and tribological assessment of PEEK/CoCr composites.Scientific reports · 2025Article
- Theoretical Investigation of Photon Interaction and X-Ray Imaging Performance of PEEK-Based Composites for Medical Implants.Polymers · 2025Article
- Biomineralized PEEK cages containing osteoinductive CaP bioceramics promote spinal fusion in goats.Bioactive materials · 2025Article
- Finite element investigation for improving chest wall reconstruction process using ceramic and polymeric implants.Scientific reports · 2025Article
- 3D-printed hip prostheses with regenerative integration: a state-of-the-art comprehensive review.Frontiers in bioengineering and biotechnology · 2025Review
- Revolutionizing Dental Polymers: The Versatility and Future Potential of Polyetheretherketone in Restorative Dentistry.Polymers · 2024Review
- Review
- DFT-based investigation of polyetherketoneketone materials for surface modification for dental implants.European journal of medical research · 2024Article
- [Research progress of magnesium and magnesium alloy implants in sports medicine].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Review
- Optimized Polymeric Membranes for Water Treatment: Fabrication, Morphology, and Performance.Polymers · 2024Review
- Progress in Nanostructured Mechano-Bactericidal Polymeric Surfaces for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2023Review
- Feasibility of 3D-Printed Locking Compression Plates with Polyether Ether Ketone (PEEK) in Tibial Comminuted Diaphyseal Fractures.Polymers · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global orthopedic market is forecasted to reach US$79.5 billion by the end of this decade. Factors driving the increase in this market are population aging, sports injury, road traffic accidents, and overweight, which justify a growing demand for orthopedic implants. Therefore, it is of utmost importance to develop bone implants with superior mechanical and biological properties to face the demand and improve patients' quality of life. Today, metallic implants still hold a dominant position in the global orthopedic implant market, mainly due to their superior mechanical resistance. However, their performance might be jeopardized due to the possible release of metallic debris, leading to cytotoxic effects and inflammatory responses in the body. Poly (ether-ether-ketone) (PEEK) is a biocompatible, high-performance polymer and one of the most prominent candidates to be used in manufacturing bone implants due to its similarity to the mechanical properties of bone. Unfortunately, the bioinert nature of PEEK culminates in its diminished osseointegration. Notwithstanding, PEEK's bioactivity can be improved through surface modification techniques and by the development of bioactive composites. This paper overviews the advantages of using PEEK for manufacturing implants and addresses the most common strategies to improve the bioactivity of PEEK in order to promote enhanced biomechanical performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.